ancient life oil cbdDecember 15, 2021
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Talk to your healthcare provider to learn more about whether CBD oil could be beneficial for you.
The FDA reports it’s only seen limited data regarding the safety of CBD. Anyone interested in consuming CBD in any form should first consult with their healthcare provider and be aware of potential risks associated with using CBD products, including liver injury, drug interactions and male reproductive toxicity.
To choose the best CBD oils of 2021, the Forbes Health editorial team analyzed data on more than 40 CBD oil products that are:
We then ranked CBD oils based on price, potency, dietary friendliness and flavor options available. Dietary friendliness means we considered the quality of the carrier oil used and whether the product is vegan and gluten-free.
Forbes Health adheres to strict editorial integrity standards. To the best of our knowledge, all content is accurate as of the date posted, though offers contained herein may no longer be available. The opinions expressed are the author’s alone and have not been provided, approved or otherwise endorsed by our advertisers.
As of 2021, CBD that comes from hemp (a type of cannabis sativa plant) that produces no more than 0.3% THC by dry weight is considered legal at the federal level. State laws vary, so it’s best to confirm any rules and regulations that apply to your area with your local and state legislation.
A growing body of research suggests CBD oil can benefit people with:
We considered a standard serving size to be 1 milliliter of CBD oil but provided CBD contents per drop as well for people experimenting to find their ideal dose. We evaluated 30-milliliter bottles when possible to keep all data comparable.
Standard drug tests don’t screen for CBD because it’s not an intoxicating substance, nor is it an illegal controlled substance. However, some CBD products contain trace amounts of THC, which can affect the results of a drug test.
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Can CBD oil impact the results of a drug test?
Is CBD oil safe?
“The rate and scale of the research just hasn’t kept pace with the interest at this point. A lot of the medical uses for cannabidiol are backed by animal studies only or really no studies. So that’s where it can be a problem.”
Here, Tieraona Low Dog, M.D., an expert on herbal medicine and women’s health, and Kevin Hill, M.D., Director of the Division of Addiction Psychiatry at Beth Israel Deaconess Medical Center and an Assistant Professor of Psychiatry at Harvard Medical School, get to the bottom of CBD tinctures’ mystique.
“Quality is always an issue, especially in a relatively young market, such as the cannabis market,” Low Dog says. And she’s right. A 2017 study published in the Journal of the American Medical Association found that out of the commercially available CBD products, only 30 percent were accurately labeled.
But first, a little CBD 101…
According to Low Dog, a tincture may offer a broader range of compounds from hemp than an oil extraction. “Consumers who are alcohol-sensitive often prefer hemp oil over tincture. While both can be used topically, hemp oil is generally easier to apply and less irritating,” she says.
So are there side effects?
Despite its relatively recent place in our collective consciousness, CBD has been at work delivering its calming agents as far back as the ‘80s by some estimates and the ancient world by others. With it, an almost endless menu of formulations has emerged—from capsules and oils to lotions and seltzer—each promising an even more effective dose of CBD than the last.
The cannabis plant has hundreds of chemicals in it, including more than 120 cannabinoids, Hill explains. Of those cannabinoids, two are most familiar: THC, which produces the euphoric effects or “high” people experience from marijuana, and cannabidiol or CBD, which has some anti-inflammatory, anti-seizure, anxiety-relieving and analgesic properties, according to Low Dog.
Tinctures, though, remain somewhat shrouded in mystery, in part because of their old-school apothecary-style packaging, but more likely because of how they’re taken: a few drops at a time, under the tongue.
“Sometimes, you will find extracts called tinctures that use glycerin, vinegar, or oil as the solvent, instead of alcohol,” Low Dog says. “These offer the advantage of being alcohol-free, but may not always offer the same potency as an alcohol-water extract.”
On that note, Hill cautions to know what you’re getting: “If you’re rubbing a CBD cream onto your skin, it’s not going to be absorbed into your bloodstream,” he says. “It can operate as a local anti-inflammatory, like other over-the-counter products… but CBD may not provide any more relief than those products, and it probably will be considerably more expensive.”
CBD tinctures are generally made from high CBD strains of hemp, with 60 to 70 percent alcohol, and are primarily used to help relieve anxiety or ease pain. “Tinctures are convenient, have a long shelf life, and are absorbed easily when taken under the tongue. The dose can be adjusted by increasing or decreasing the number of drops taken,” notes Low Dog.
“At the end of the day [CBD] is a fairly safe compound,” Hill says. “Although, we still need to know a lot more about it, like how it interacts with other medications people may be taking and what are the long-term effects,” he adds. And perhaps his biggest concern: “Sometimes people want to use it instead of evidence-based treatment and that can be a problem clinically in certain situations.”
And though there’s a lot of promise with CBD preparations of all kinds, Hill says there’s still a lot of research to be done.
An herbal tincture is made by using a mixture of alcohol and water to extract compounds from a plant—in this case, the cannabis plant.
At a plant level, the two chemicals operate as opposites, with CBD acting as a buffer of sorts to the effects of THC. “It’s sort of a ying and yang. THC is responsible for the high and CBD doesn’t do that,” Hill explains.
What is it?
“Many of them had more CBD than they were supposed to and many had less; some had none,” Hill notes. He suggests shopping organic—as a bio-accumulator, the cannabis plant will be affected by heavy metals and contaminants in soil—and broad-spectrum, meaning it includes the full range of phytocannabinoids, minus the THC.