cbd and thyroid cancerDecember 15, 2021
Anxiety is one of the major contributors to sleep deprivation, which is one of the reasons why people use CBD oil for sleep disorders. Aside from that, CBD influences the functioning of our circadian rhythm.
Researchers have discovered the presence of CB1 receptors on the thyroid gland of animal models. These receptors regulate the production of two thyroid hormones, T3 and T4.
Humans and all animals — except for insects — have an endocannabinoid system (ECS). The ECS is our major regulatory network that controls a variety of biological processes, including mood, memory, immune response, body temperature, appetite, fertility, sensory perception, neuroprotection, and more.
A 2015 study found significant concentrations of CB1 and CB2 cannabinoid receptors in the thyroid glands. These receptors were associated with the shrinkage of thyroid tumors, showing promise as potential blockers of the spread of malignant cells on the gland (1).
However, the amount of research is insufficient to define CBD as an effective treatment for thyroid health problems; we need more clinical trials to come to this conclusion.
CBD Oil for Metabolism & Low Energy Levels.
Doctors use special tests to diagnose thyroid imbalances, including biopsies and imaging scans, such as ultrasound or iodine screenings. Patients are also asked to run a test for T3, T4, and thyroid-stimulating hormone (TSH) to search for thyroid imbalances.
In other words, CBD regulates our sleep-wake cycle. Taking lower doses in the morning may not only reduce anxiety but also improve energy and focus, thus increasing productivity (7). With heightened daily alertness throughout the day, our body starts to receive signals that it has done enough work for the day and it’s time to go to bed. Consistent supplementation with CBD can help the body manage its melatonin levels, which is a hormone that helps the body set the right gears in motion to fall asleep faster.
Nina created CFAH.org following the birth of her second child. She was a science and math teacher for 6 years prior to becoming a parent — teaching in schools in White Plains, New York and later in Paterson, New Jersey.
The THS is a figure that measures the amount of thyroxine (T4) that the thyroid gland should release.
Problems with thyroid health often involve episodes of pain, especially in the joints and muscles. CBD has been shown to mitigate pain signaling through the indirect interaction with opioid and vanilloid receptors in the brain, which modulate pain perception (11). CBD also has strong anti-inflammatory properties, which could potentially help reach the underlying cause of pain (12).
Overproduction or underproduction of the thyroid hormones may ravage a person’s health over time. Thyroid disorders are challenging to treat due to the difficulties in diagnosis. Thyroid conditions can have several underlying causes associated with physical functions.
One of such mechanisms is the agonism of the 5-HT1A receptor, which controls serotonin secretion. Serotonin is a neurotransmitter that manages feelings of happiness, well-being, and relaxation (4).
Thyroid dysfunctions can result in a range of symptoms that stem from imbalances in the above functions.
Studies have shown that CBD also helps us stay longer in the deep sleep stage while reducing REM disorders.
CBD Oil for Anxiety.
If you want to avoid CBD-drug interactions, we encourage you to consult a doctor before buying a CBD product for thyroid health.
However, we still need more quality studies on humans to support preclinical findings.
Symptoms of thyroid disorders include:
CBD indirectly engages with these receptors, which would explain their potential for managing thyroid disorders, especially the problems of hormonal imbalances.
In a study published in the Journal of Experimental Medicine, the authors found that CBD and its modified equivalents were effective in easing chronic inflammatory and neuropathic pain in rats (2).
Most hypothyroidism or hyperthyroidism cases can be dealt with a properly adjusted dose of thyroid hormone. Healthy nutrition and an active lifestyle can also contribute to the mitigation of symptoms.
Studies on CBD and Thyroid Health.
When you take CBD along with thyroid medication, the aforementioned interaction may result in either subtherapeutic effects or toxic levels of the drugs in the bloodstream.
We have looked into many forums for patients with thyroid disorders who also take CBD for their conditions. The vast majority reports little to no side effects, but they underline the importance of having a 2-hour gap between one compound and the other.
The topic of CBD-drug interactions is a complex one. CBD is known to inhibit the activity of the Cytochrome p450 system, a set of enzymes responsible for metabolizing the active ingredients in medications. This applies to both prescription and OTC meds.
These hormones play an important role in modulating energy levels, body weight, temperature, as well as the growth of hair, nails, and skin cells.
A 2013 review of the existing studies on cannabis and metabolism showed that regular cannabis users have lower fasting insulin resistance, lower blood sugar levels, and smaller waist circumference. However, the review looked into the efficacy of cannabinoids on metabolism in general, not CBD alone (10).
The thyroid is a critical endocrine gland that is situated at the base of the neck, wrapping around the front of the trachea. The thyroid produces a variety of hormones that influence bodily functions, such as metabolic rate, bone density, heart health, and muscle strength.
Fat browning refers to the conversion of white fat cells to brown fat cells (9). The brown cells are more effective when it comes to converting fat to energy, helping individuals burn more calories as a result. On top of that, cannabinoids may have a positive effect on metabolism through improving the body’s sensitivity to insulin and reducing blood sugar levels as a result.
For underactive thyroid, T4 replacement medications like levothyroxine and Synthroid are common. For hyperthyroidism (overactive thyroid), treatments that reduce hormone secretion are necessary.
In other words, it won’t get you high. Individuals often use cannabis due to its lack of mind-altering effects. They want a natural treatment, but they don’t want to be under the influence.
Most people who use CBD for thyroid disorders often use a single high-quality CBD oil. CBD oil may address a variety of thyroid malfunctions. These malfunctions include hypothyroidism, hyperthyroidism, goiter, thyroiditis, and thyroid storm. Of course, the question is – how well does it work?
Conventional Thyroid Disorder Treatments (Not CBD)
Untreated hypothyroidism in pregnant women can lead to a litany of issues. These issues include miscarriage, preterm delivery, and growth/developmental problems.
Lifestyle changes can sometimes be effective in minimizing these symptomatic conditions. Yet, the thyroid network is a very complex web of cellular machinery. Because of this, it can be difficult to pinpoint how to induce positive changes.
There are many conventional treatment options for thyroid conditions. These treatments often include pharmaceutical medications.
The American Thyroid Association (ATA) estimates that thyroid disorders currently affect up to 20 million Americans. Furthermore, as much as 12% of the U.S. population will at some point in their lives develop a thyroid condition.
Exploring the advantages and d…
In this article, we discuss what the thyroid does and the symptoms of a dysfunctional thyroid gland. We’ll also go over the use of CBD for thyroid disorders and take a look at academic research on the topic.
Thyroid glands that release either too much (hyperthyroidism) or too little (hypothyroidism) hormone can be catastrophic to organ functioning and to your health and well-being. Specific disorders of the thyroid can include things like:
Why CBD for Thyroid – What About ‘Regular’ Marijuana?
These treatments include radioactive iodine and antithyroid drugs like methimazole and propylthiouracil (PTU). While effective, these drugs can cause severe side effects in the liver and immune system.
Because thyroid conditions can cause so many malfunctions in the body, it can be difficult to detect a specific disorder. There are certain tests to check for thyroid imbalances. These tests include biopsies, imaging scans (such as ultrasounds or iodine scans), and blood tests that check for proper levels of T3, T4, and thyroid-stimulating hormone (TSH).
This is why people are beginning to talk about CBD for thyroid disorders. By acting upon the endocannabinoid system, CBD can work to regulate internal homeostasis on the whole-body level.
Thyroid disorders can cause many different problems within the body and brain. These problems can impact the quality of an individual’s day to day life and can include things like:
Plus, women are statistically five to eight times more likely to develop a thyroid problem than men.
Living with Thyroid Disorders.
Most are choosing to go with high-quality CBD oil as a daily supplement. Oils act as molecular carriers. They are able to “hold” more cannabidiol molecules by volume than other forms of CBD (i.e., gummies or capsules).
Also, the general properties of CBD may be able to help with the effects of thyroid disorders. CBD is a powerful anti-inflammatory. Dozens of studies state the role of cannabinoids in reducing organ and tissue inflammation.
This is why most CBD products come from industrial hemp – a cannabis plant that contains less than 0.3% THC. When cannabis contains a THC content higher than 0.3%, it is determined to be “marijuana.” This can be confusing as many people use the terms hemp and marijuana interchangeably.
More clinical trials can determine how effective CBD is for thyroid disorders. Thus far, research of CBD’s relationship with hormone activity is promising.
If you’re wondering why so many folks are talking about CBD for thyroid disorders and not THC, you’re not alone. Simply put, the overwhelming interest stems from the fact that CBD is non-psychoactive.
Millions of people worldwide smoke marijuana for its therapeutic benefit. This is the basis of the medical marijuana market. Hemp-based products often boast the benefits of cannabis without the high.
CBD oil can adversely affect liver function. In fact, this is on the warning label for Epidiolex.
All drugs and dietary supplements are regulated by the FDA. But as long as CBD oil is not marketed as a medicine or a dietary supplement, producers can get around that policy. So right now, CBD oil is very unregulated. That means it’s hard to know how much CBD or THC is really in any given product. Certain hemp CBD products have been found to contain significantly less CBD or more THC than advertised.
This is very important for cancer patients to understand, as many people think CBD oil is not a medicine. They think of it more as a vitamin or a supplement, so they might not let their doctors know they’re using it. Patients might not realize it can be potentially harmful. So, it’s very important to tell your doctor if you’re using CBD oil.
Does CBD oil have any side effects?
Other sorts of substances have been found in CBD products, too, such as dextromethorphan, which is an ingredient in cough medicines. Heavy metals like lead and arsenic, pesticides and mold have also been found in CBD products.
There have been reports that cannabinoids like THC and CBD may be helpful for nausea and vomiting and anorexia, as well as neuropathy, anxiety, depression and insomnia. Synthetic cannabinoids like dronabinol have been approved for use with chemotherapy-induced nausea and vomiting, but have not been shown to be superior to conventional anti-nausea medications.
Have any products using CBD-oil been approved by the FDA to treat anything?
In terms of purity, THC and CBD are both extracted from hemp and marijuana using essentially similar processes. But trace amounts of THC could still end up in CBD oil. And if the THC is at a high enough concentration, it could produce the psychoactive effects that THC is known for.
But what is CBD oil exactly, and how does it affect cancer patients? Can it really treat — or even cure — cancer or relieve its symptoms? To separate fact from fiction, we spoke with our Kimberson Tanco, M.D. Here’s what he wants cancer patients to know.
It comes in many forms: oils that are dropped under the tongue, roll-ons that are applied to the skin and even solutions for vaping. Some producers extract CBD oil and add it into foods to create edible products.
Marijuana and hemp are both varieties of the cannabis sativa plant. Both contain cannabidiol (CBD) and tetrahydrocannabinol (THC) — the two most-common, known active ingredients.
And in lab studies, CBD has been shown to inhibit certain enzymes responsible for the metabolism of drugs, such as CYP2D6 and CYP3A4. This can affect how drugs work and affect our bodies, either by reducing their efficiency or making them more dangerous. This includes chemotherapy and other medications.
Have any CBD-oil derived products been approved by the U.S. Food and Drug Administration (FDA) to treat cancer, its symptoms, or the side effects caused by its treatment?
Studies on a certain CBD manufacturer showed its products were contaminated with a chemical known as 5F-ADB, which mimics THC. 5F-ADB is classified by the U.S. Drug Enforcement Administration as illegal, potentially addictive and with no accepted medical use.
Quality, cleanliness and regulation are the biggest concerns.
State laws vary. In Texas, the Compassionate Use Act allows for the use of medical marijuana for certain conditions. Originally only for intractable epilepsy, the law was expanded this year to include cancer and certain neurodegenerative conditions, such as Parkinson’s and multiple sclerosis.
What, if anything, can CBD oil do to alleviate the symptoms of cancer or the side effects of cancer treatment?
Finally, there have been some reports of people getting infections after using CBD and cannabis products. This is especially concerning for immunocompromised patients, who are already susceptible to bacterial and fungal infections.
CBD oil (cannabidiol) is everywhere these days. Once available only at novelty or vitamin shops, it’s now also at your local grocery store, pharmacy or even yoga studio.
What’s the most important thing cancer patients should know about CBD oil?
At the national level, any product of marijuana — including CBD — is still technically illegal when used medically. Although the 2018 Farm Bill legalized the production of hemp nationally, that’s only permitted if it’s not marketed for medical use or as a dietary supplement. CBD products intended for medical use should undergo an FDA review process.
Yes. Epidiolex. It was originally approved in 2018 for the treatment of two conditions, both related to epilepsy: Lennox-Gastaut syndrome and Dravet syndrome. But aside from Epidiolex, no CBD product has been approved by the FDA for any other medical purpose.
There’s still a lot to learn. So always let your health care team know if you are using CBD oil. That way, we can make sure nothing interacts adversely with your cancer treatments or other medications.
Is there any truth to the claims that CBD oil can cure cancer?
Third, the plant itself may have higher levels of THC than expected. This could be due to its environment, prolonged flowering periods or cross-contamination and pollination between male and female plants, resulting in offspring with higher THC content. This especially affects hemp plants, which should have less than 0.3% THC levels.
But the application of this law is pretty jumbled right now. So, while it may be legal to use CBD in a state like Colorado or Alaska, if an employer follows federal regulations, the standardization and quality of a CBD product matters. Because if there’s even a small percentage of THC in that product, then a drug test might come back positive. And this could result in legal issues for the user.
The main difference is that hemp has far less THC than a typical marijuana plant. And unlike THC, CBD is not a psychoactive agent, so there’s less possibility that it will cause the same mental confusion, drowsiness or hallucinations that often come with THC.
What is CBD oil, and how does it differ from marijuana and hemp?
Right now, no. There is no evidence that CBD oil can cure cancer.
Is CBD oil even legal?