cbd and thyroid medicationDecember 15, 2021
CBD indirectly engages with these receptors, which would explain their potential for managing thyroid disorders, especially the problems of hormonal imbalances.
Humans and all animals — except for insects — have an endocannabinoid system (ECS). The ECS is our major regulatory network that controls a variety of biological processes, including mood, memory, immune response, body temperature, appetite, fertility, sensory perception, neuroprotection, and more.
The potential benefits of CBD for thyroid health are expressed through their interaction with the body’s ECS and its two types of receptors — CB1 and CB2.
CBD Oil for Sleep.
CBD is a powerful anti-inflammatory compound. Multiple studies have proven the role of cannabinoids in reducing organ and tissue inflammation.
Scientists believe that oral forms of CBD — such as CBD oil or capsules — produce better effects from the symptoms caused by internal imbalances, especially when it comes to anxiety and depression. On the other hand, topical products are more effective for problematic areas on the body.
A growing number of studies suggest that CBD and other cannabinoids can be used for dealing with the symptoms associated with thyroid conditions, including skin problems, inflammation, pain, anxiety and depression, weight gain, and low energy levels.
Fat browning refers to the conversion of white fat cells to brown fat cells (9). The brown cells are more effective when it comes to converting fat to energy, helping individuals burn more calories as a result. On top of that, cannabinoids may have a positive effect on metabolism through improving the body’s sensitivity to insulin and reducing blood sugar levels as a result.
Symptoms of thyroid disorders include:
Although research on the efficacy of thyroid disorders is in its infancy, current studies regarding CBD’s influence on hormonal activity is promising.
A high-quality CBD oil may address a variety of thyroid dysfunctions. This underperformance includes hypothyroidism, hyperthyroidism, goiter, thyroiditis, and thyroid storm.
Studies on CBD and Thyroid Health.
Having read about potential CBD-drug interactions might have you wonder whether you should totally ditch CBD when taking thyroid medications, such as levothyroxine.
The endocrine system is made of a number of glands in the body that produce and secrete hormones for different functions.
Anxiety is one of the major contributors to sleep deprivation, which is one of the reasons why people use CBD oil for sleep disorders. Aside from that, CBD influences the functioning of our circadian rhythm.
CBD can also temporarily lower blood pressure, allowing the user to take deeper breaths. This, in turn, can have a positive effect on our physical response to stress (6).
Due to its interaction with the endocannabinoid system (ECS), CBD allows individuals to take on an alternative route to managing the level of thyroid hormones in the blood. This, in turn, holds promise for patients with thyroid disorders who are apprehensive about conventional methods.
CBD Oil for Metabolism & Low Energy Levels.
Levothyroxine is the most popular thyroid medication. Like many other pharmaceuticals, it is processed by the same group of enzymes as CBD.
Most hypothyroidism or hyperthyroidism cases can be dealt with a properly adjusted dose of thyroid hormone. Healthy nutrition and an active lifestyle can also contribute to the mitigation of symptoms.
In the first scenario, your primary medicine may lose efficacy and thus fail to provide the desired effects.
Thyroid dysfunctions can result in a range of symptoms that stem from imbalances in the above functions.
The thyroid is a critical endocrine gland that is situated at the base of the neck, wrapping around the front of the trachea. The thyroid produces a variety of hormones that influence bodily functions, such as metabolic rate, bone density, heart health, and muscle strength.
In a study published in the Journal of Experimental Medicine, the authors found that CBD and its modified equivalents were effective in easing chronic inflammatory and neuropathic pain in rats (2).
Researchers from Penn State College of Medicine evaluated existing information on five prescription CBD and delta-9-tetrahydrocannabinol (THC) cannabinoid medications: antinausea medications used during cancer treatment (Marinol, Syndros, Cesamet); a medication used primarily for muscle spasms in multiple sclerosis (Sativex, which is not currently available in the US, but available in other countries); and an antiseizure medication (Epidiolex). Overall, the researchers identified 139 medications that may be affected by cannabinoids. This list was further narrowed to 57 medications, for which altered concentration can be dangerous. The list contains a variety of drugs from heart medications to antibiotics, although not all the drugs on the list may be affected by CBD-only products (some are only affected by THC). Potentially serious drug interactions with CBD included.
Products containing cannabidiol (CBD) seem to be all the rage these days, promising relief from a wide range of maladies, from insomnia and hot flashes to chronic pain and seizures. Some of these claims have merit to them, while some of them are just hype. But it won’t hurt to try, right? Well, not so fast. CBD is a biologically active compound, and as such, it may also have unintended consequences. These include known side effects of CBD, but also unintended interactions with supplements, herbal products, and over-the-counter (OTC) and prescription medications.
Many drugs are broken down by enzymes in the liver, and CBD may compete for or interfere with these enzymes, leading to too much or not enough of the drug in the body, called altered concentration. The altered concentration, in turn, may lead to the medication not working, or an increased risk of side effects. Such drug interactions are usually hard to predict but can cause unpleasant and sometimes serious problems.
CBD can alter the effects of other drugs.
Absolutely. Inhaled CBD gets into the blood the fastest, reaching high concentration within 30 minutes and increasing the risk of acute side effects. Edibles require longer time to absorb and are less likely to produce a high concentration peak, although they may eventually reach high enough levels to cause an issue or interact with other medications. Topical formulations, such as creams and lotions, may not absorb and get into the blood in sufficient amount to interact with other medications, although there is very little information on how much of CBD gets into the blood eventually. All of this is further complicated by the fact that none of these products are regulated or checked for purity, concentration, or safety.
While generally considered safe, CBD may cause drowsiness, lightheadedness, nausea, diarrhea, dry mouth, and, in rare instances, damage to the liver. Taking CBD with other medications that have similar side effects may increase the risk of unwanted symptoms or toxicity. In other words, taking CBD at the same time with OTC or prescription medications and substances that cause sleepiness, such as opioids, benzodiazepines (such as Xanax or Ativan), antipsychotics, antidepressants, antihistamines (such as Benadryl), or alcohol may lead to increased sleepiness, fatigue, and possibly accidental falls and accidents when driving. Increased sedation and tiredness may also happen when using certain herbal supplements, such as kava, melatonin, and St. John’s wort. Taking CBD with stimulants (such as Adderall) may lead to decreased appetite, while taking it with the diabetes drug metformin or certain heartburn drugs (such as Prilosec) may increase the risk of diarrhea.
The researchers further warned that while the list may be used as a starting point to identify potential drug interactions with marijuana or CBD oil, plant-derived cannabinoid products may deliver highly variable cannabinoid concentrations (unlike the FDA-regulated prescription cannabinoid medications previously mentioned), and may contain many other compounds that can increase the risk of unintended drug interactions.
CBD has the potential to interact with many other products, including over-the-counter medications, herbal products, and prescription medications. Some medications should never be taken with CBD; the use of other medications may need to be modified or reduced to prevent serious issues. The consequences of drug interactions also depend on many other factors, including the dose of CBD, the dose of another medication, and a person’s underlying health condition. Older adults are more susceptible to drug interactions because they often take multiple medications, and because of age-related physiological changes that affect how our bodies process medications.
People considering or taking CBD products should always mention their use to their doctor, particularly if they are taking other medications or have underlying medical conditions, such as liver disease, kidney disease, epilepsy, heart issues, a weakened immune system, or are on medications that can weaken the immune system (such as cancer medications). A pharmacist is a great resource to help you learn about a potential interaction with a supplement, an herbal product (many of which have their own drug interactions), or an over-the-counter or prescription medication. Don’t assume that just because something is natural, it is safe and trying it won’t hurt. It very well might.
Doubling up on side effects.
Does the form of CBD matter?
Perhaps searching can help.
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