cbd bipolarDecember 15, 2021
Some of the patients she spoke to still elected to use CBD oil, instead of other treatments that have been proven to be effective for conditions like bipolar disorder, she told The Current's guest host Matt Galloway.
The cannabis extract is non-psychoactive and does not produce a high. It has been touted as a relief for everything from chronic pain to insomnia.
In the course of her research, Gobbi has spoken with the patients using CBD oil without medial oversight. She warned them that there has been very little testing into its effect on humans, and there isn't much scientific data to support the health claims.
People suffering from serious conditions are forgoing doctor visits in favour of self-medicating with CBD oil, according to one "very worried" researcher.
"A lot of patients have contacted me from all over Canada, and [are] using cannabidiol to treat depression, bipolar disorder," said Dr. Gabriella Gobbi, a psychiatrist at McGill University's faculty of medicine and the McGill University Health Centre.
More clinical trials needed into cannabidiol's alleged health benefits: researcher.
"It means they're not treated at all, so this is very, very worrisome in our society because people are not cured at the end of the day."
Retailers were struggling to keep CBD oil on the shelves earlier this year, after anecdotal endorsements helped boost its popularity. But Gobbi warned that positive stories, without scientific testing, could be a "placebo effect."
Bipolar affective disorder is often poorly controlled by prescribed drugs. Cannabis use is common in patients with this disorder and anecdotal reports suggest that some patients take it to alleviate symptoms of both mania and depression. We undertook a literature review of cannabis use by patients with bipolar disorder and of the neuropharmacological properties of cannabinoids suggesting possible therapeutic effects in this condition. No systematic studies of cannabinoids in bipolar disorder were found to exist, although some patients claim that cannabis relieves symptoms of mania and/or depression. The cannabinoids Delta(9)-tetrahydrocannabinol (THC) and cannabidiol (CBD) may exert sedative, hypnotic, anxiolytic, antidepressant, antipsychotic and anticonvulsant effects. Pure synthetic cannabinoids, such as dronabinol and nabilone and specific plant extracts containing THC, CBD, or a mixture of the two in known concentrations, are available and can be delivered sublingually. Controlled trials of these cannabinoids as adjunctive medication in bipolar disorder are now indicated.