cbd dose for osteoporosisDecember 15, 2021
Research also suggests that CBD’s ability to enhance the body’s endocannabinoid system can also enhance the strength of bones in the body. The endocannabinoid system describes how the body’s own neurotransmitters affect feelings of both physical and mental pain or discomfort. Two of the body’s receptors are known as CB1 and CB2, which can impact the bone metabolism in the body.
Let’s look at some facts about osteoporosis. Research shows that over 200 million people suffer from weakened or deficient bone structure, and many of those people are, not surprisingly, elderly people. But concerns about bone density can begin as early as one’s 40s or 50s.
But as modern science uncovers new medicinal possibilities, researchers are testing the validity of using CBD oil for osteoporosis cases. The theory states that, as a natural remedy, CBD oil can reinforce the structural integrity of weakened bones to promote healthy active living.
Can CBD Oil Help Osteoporosis.
CBD has been known to improve the quality of life for seniors, both male and female. Those insights, combined with ongoing research into the effects of CBD and bone healing, suggest more senior citizens can benefit from CBD-infused products.
The endocannabinoid system can be weakened if the body fails to naturally produce enough endocannabinoids. But the natural compounds in CBD oil are virtually identical to the body’s natural endocannabinoids. That means, in the event that the system is compromised, healthy doses of CBD oil can increase the volume of endocannabinoids in the body, which can strengthen bones and accelerate the healing of bone fractures.
CBD has been known to improve the effects of high blood pressure and neuropathy in people coping with underlying symptoms of those conditions. Additionally, CBD has improved the mental health and wellbeing of people living with illnesses. Most prominently, CBD has altered and improved the livelihoods of those living with anxiety or depression.
If you’re considering taking CBD oil for osteoporosis or for any underlying condition, speak with your doctor about your intentions and ask for advice. Many doctors are experienced in these conversations and, given he or she should be well aware of your medical history and overall health, you should come to a rational recommendation on an optimal CBD dosage.
CBD oil is a natural remedy that has become widely associated with the health and wellness industry. It’s now available in the form of oils, lotions, and even the occasional edible to provide as smooth and simple of a dose as possible. The ability for CBD to suppress receptors that trigger pain in the body can drastically improve the overall quality of life for people who choose to take regular doses.
Osteoporosis occurs when the bone structure in the human body is compromised. According to the National Osteoporosis Foundation, it occurs when the integrity of the bones weakens as a result of the body producing too much bone, too little bone, or both.
The studies show that CBD can accelerate the body’s ability to heal and enhance the strength of broken or fractured bones. Scientists prescribed 5mg of CBD oil to a lab rat that was suffering from alveolar bone loss. At the end of the 30 day trial period, the tests showed decreased alveolar bone loss in the rat and the doctors also confirmed decreased neutrophil migration in the gingival tissues, a medical term describing the body’s gums.
CBD and Bone Density.
Osteoporosis is a very painful and difficult condition to live with every day. Anything that can enhance bone strength and bone density is worth considering to alleviate the worst symptoms associated with that pain.
However, patients that have been prescribed CBD oil consult with their primary doctors about how to calculate an optimal amount of oil for treatment. Doses have ranged from as low as 5mg per day to over 100mg per day. The body mass and overall health of the patient plays a large role in determining how large a dose is recommended by physicians.
Given the physical pain and debilitating effects of compromised bone integrity, it’s not unlikely that osteoporosis patients succumb to mental disorders like anxiety or depression. There’s room to believe that CBD oil can improve both the physical and mental livelihoods of people coping with damaged or weakened bone structure.
When substituting for endocannabinoids, CBD has the ability to block or suppress receptors in the body that trigger physical pain or cause mental imbalances. The American Society for Bone and Mineral Research indicates that, in one particular trial, CBD blocked the GRP55 receptor, which dramatically reduced the number of cells that degrade bone integrity.
Methods to treat osteoporosis involve a number of medically approved drugs known as bisphosphonates. Bisphosphonates are typically made available in the form of Fosamax (alendronate), Actonel (risedronate), or Boniva (ibandronate).
CBD and Bone Healing.
However, the rate of mortality caused by osteoporosis is significantly higher in men than in women. That means that, while more women may be diagnosed with osteoporosis symptoms, the condition is, often, fatal for men.
In fact, the data shows 1 out of 3 women over the age of 50 are prone to osteoporosis. Approximately 1 in 5 men in the same age group will struggle with weakened bone structure as well.
Based on the preliminary research in numerous medical journals, there is plenty of evidence suggesting CBD is a healthy treatment for osteoporosis. Human trials are still necessary to verify the effects of CBD oil for osteoporosis, but there is precedent for successful human clinical trials involving CBD and other medical challenges.
An article with the Harvard Medical School specifically states that scientists have yet to determine the most effective therapeutic dose of CBD for any particular medical condition, including osteoporosis. This is, in large part, due to the fact that there are still so many unknowns about CBD oil. The medical community agrees, in principle, that CBD does provide therapeutic benefits for patients. But there is no formal agreement on the ideal dosage.
Do consult with your doctor if you intend to take CBD oil. Make sure there are no underlying conditions in your medical history that could compromise your health and wellbeing. If given the all-clear, you may find that using CBD oil for osteoporosis results in a much healthier and happier livelihood from that point onward.
CB2 is expressed predominantly in osteoclasts (bone-resorbing cells) and osteoblasts (bone-forming cells). This kind of cannabinoid receptor is necessary for the regulation of your bone metabolism. Physiologically, it is important to keep a balance between osteoclasts and osteoblasts as it would maintain optimum bone health. As people age, this balance would be impaired, and result in bone fractures or loss of bone density.
The Endocannabinoid System (ECS) plays an essential role in the regulation of osteoclast and osteoblast activities 5 . This means if any problem happens in this area, it might lead to a number of conditions, including osteoporosis. There is also evidence to show your ECS might determine the development of a low bone mass 6 . Indeed, a lack of the endocannabinoid receptors in your brain has been linked to a higher turnover of bone.
What’s more, CBD can inhibit several enzymes such as FAAH and increase the effects that they would exert on these cannabinoid receptors. As a result of these effects, researchers have suggested that CBD is effective and helpful in lowering the risks of bone problems and enhancing health.
Recent studies have proven that the use of Cannabidiol (CBD) oil can have positive effects on these receptors, thus alleviating symptoms as well as slowing the progression of osteoporosis.
There are typically not many symptoms in the early stages of Osteoporosis. Once your bones have been weakened by the bone loss, you may have signs and symptoms that include:
In general, the ECS consists of cannabinoid receptors that are activated by several elements like CBD. The endocannabinoids are basically generated and degraded by a few types of enzymes, this giving this system a role in controlling some essential activities. Consequently, reduced numbers of endocannabinoid receptors are linked to the development of osteoporosis.
CBD oil is available in various forms and concentrations, including liquid or thick paste, oil, capsules, gum or candy, salves, sprays or drops, and vapor.
This element might delay the formation of your bones and the bone density, adjust the rate of reabsorption and lead to some bone issues.
A published study in 2015 by researcher Kogan Niemand 10 has found that when mice were treated with CBD oil, the maximal loads on their bones significantly increased. Also, he discovered that using CBD could speed up the process of healing fractures or broken bones, as well as slow down the loss of bone density.
What are the Benefits of Using CBD oil for Osteoporosis?
Another study by Idris Al focused on the important part of cannabinoid receptors in treating osteoporosis 9 . The results suggested that CBD is likely to affect bone metabolism and ligands. Therefore, these products can be used for bone fractures and other issues as they may be applied to exploit the cannabinoid receptors for targeting anabolic therapy and anti-resorptive.
According to the International Osteoporosis Foundation 1 , this condition affects an estimated 75 million people in Europe, the United States, and Japan. It is estimated to affect 200 million women worldwide – approximately one-tenth of women aged 60.
As a rule of thumb, the dosage of CBD oil or for osteoporosis treatments can vary a lot depending on the level of intensity. It is advisable to start small and increase the CBD dosage gradually until you get the desired results. A standard dose of between 10mg and 100mg of CBD per day is recommended by the CBD experts Leinow and Birnbaum in thier book “CBD: A Patient’s Guide to Medicinal Cannabis”.
Women are more likely to develop Osteoporosis. This is because they can quickly lose bone mass in the first couple of years after menopause.
The Endocannabinoid System & Bones.
CB2 agonists like cannabidiol (CBD) could be used to modulate the functions of these receptors 2 . They can improve the activity and count of osteoblasts while inhibiting the expression of osteoblasts and the proliferation of osteoclasts. These elements can also stimulate the formation of Endocortical bones, suppress bone losses and maintain a normal mass of bone. CB1 receptors, on the other hand, can be activated to inhibit a chemical known as norepinephrine 3 .
Essentially, your body might keep “retiring” old bone cells without producing enough new ones for replacement. However, if these receptors could be stimulated with the help of cannabidiol (CBD), the bones are more likely to maintain its function even after many years.
An in-depth guide of how to dose your CBD has been given in the book CBD: A Patient’s Guide to Medicinal Cannabis by Leinow and Birnbaum 7 . The authors have introduced their Step-Up Method , where they recommend different types of dosage according to weight and condition. To find out how to follow Leinow and Birnbaum’s guide, read our post on CBD dosage.
Other risk factors could include:
A study by French scientists has suggested that human bones come with a higher level of endocannabinoids and ligands than brain cells 8 . Also, a naturally generated cannabinoid in our body named Anandamide could have an effect on the bone tissues. Anandamide helps to bind to those CB2 receptors. They also pointed out that CBD can imitate Anandamide, thus positively affecting bone health in those people who suffer from osteoporosis.