cbd heart arrhythmiaDecember 15, 2021
Heart health is one of the areas being explored to determine the therapeutic health benefits of cannabidiol (CBD). Nearly 655,000 Americans die from heart disease every year, accounting for one in every four deaths.
Heart failure is a serious health condition in which the heart isn’t pumping the way it should be. The body depends on the heart’s pumping action to deliver oxygen and nutrient-rich blood to all of its cells.
Vaping CBD is a fast way of delivering CBD into your system, but it is not recommended for individuals with heart disease. Vaping is associated with lung damage, and research shows it causes an increased risk in developing cardiovascular disease.
What to Know About CBD for Heart Failure, Cholesterol, and Blood Pressure.
Read on to learn more about CBD’s benefits for the heart, what CBD oil is, side effects, and forms of CBD oil.
CBD is perhaps best known for its anti-inflammatory properties. Research suggests that inflammation may be at the root of many chronic illnesses. Heart disease is associated with inflammation. Inflamed blood vessels make it harder for the heart to pump blood throughout the body.
With so many CBD options available, shopping for the right product can be an overwhelming experience. Some important things to keep in mind when buying CBD include:
Jeffrey S. Lander, MD, is a board-certified cardiologist and the President and Governor of the American College of Cardiology, New Jersey chapter.
Obesity is one of the leading causes of congestive heart failure, which is one reason why it is important to maintain a healthy weight for optimal heart health. There is some evidence to suggest that CBD may help maintain a healthy weight.
Heart failure has a number of causes, including genetics, other medical conditions (e.g., anemia, diabetes, sleep apnea), and lifestyle (e.g., smoking, obesity).
CBD has anti-inflammatory, antioxidative properties that may help reduce risk factors that can lead to heart disease. It may also be helpful in reducing the risk of related conditions, such as stroke.
If you’re just starting off with CBD, try a small dose first. Watch for any side effects. If you wish, you can slowly increase your dosage (no more than 5 to 10 mg increase at a time) until you find the dosage that is right for you.
A growing body of evidence shows that dysregulated ECS is associated with a number of cardiovascular diseases. Whether you have a heart condition or want to prevent heart disease, CBD may boost your endocannabinoid system to help it regulate the cardiovascular system.
Speak with your doctor before trying CBD, particularly if you are on any other medications or dietary supplements. Your doctor can let you know if it is safe to take, and may have product and/or dosage recommendations.
There are a number of CBD types to choose from. Understanding these differences can help you choose which type is best for your needs. These types include:
Heart disease is an umbrella term that refers to several types of heart conditions. Heart disease may involve the heart valves, arteries, and heart rate, leading to heart failure.
Both CBD and THC interact with the endocannabinoid system (ECS) in the body. The ECS is a complex biological system that impacts many of the body’s functions, including appetite, memory, mood, and sleep. Researchers are learning that the endocannabinoid plays a role in the function of the cardiovascular (heart) system.
One study found that CBD promotes the browning of white fat cells, which aids in converting the fat into burnable calories. This is beneficial because brown fat cells contain more mitochondria than white fat cells, which helps burn calories. White fat cells contain droplets of fat that accumulate around the body and can lead to obesity.
CBD cannot cure heart disease or congestive heart failure, but it is being studied for ways it may help reduce symptoms or prevent heart disease. However, CBD has not been shown in large studies to prevent diseases that lead to heart failure.
There is ongoing research into the use of purer forms of CBD for a variety of conditions, including heart and circulatory diseases and, in particular, diseases of the heart muscle, including myocarditis and some types of cardiomyopathy.
Professor Sumnall argues that while it could be effective for some people, in some of these cases the results could be caused by the placebo effect (where the patient’s belief in a treatment makes them feel better). The placebo effect can be powerful, but Professor Sumnall warns that if people try CBD oil instead of speaking to their doctor, it could cause a problem.
The choice of CBD products has exploded recently: you can buy oils, capsules, muscle gels, sprays and oral drops, as well as beer, tea, sweets, hummus and even CBD-infused clothing.
A 2018 report by the World Health Organization suggested that CBD may help treat symptoms relating to conditions such as cancer, Parkinson’s disease, multiple sclerosis (MS), anxiety, depression, insomnia and Alzheimer’s disease.
Prices can be high: a 500mg bottle of CBD oil oral drops could set you back as much as £45. Not that this has put people off: over the past two years, sales of CBD have almost doubled in the UK, putting regular users at an estimated quarter of a million.
Can CBD help the heart?
Some of this work is still in animals, and much more research is needed before we can definitively say that CBD can help in this area.
But so far, Professor Sumnall points out, CBD products in shops are marketed as food supplements, not medicines, so none of them have gone through this process.
CBD is the latest health craze to sweep the high street, with claims it can help everything from chronic pain and inflammation to anxiety. But what is CBD, and can it really help the heart? Emily Ray finds out.
CBD, or cannabidiol, is a chemical that’s extracted from the leaves and flowers of the cannabis plant. Cannabis itself is an illegal class B drug, as is the compound THC (tetrahydrocannabinol) which it contains. But pure CBD isn’t illegal, as it doesn’t cause the intoxicating effects of cannabis.
Inflammation is part of the process that leads to many diseases, including coronary heart disease, high blood pressure and stroke, and there is some evidence that CBD has anti-inflammatory properties. Other studies have suggested that CBD can have a protective effect on the heart: this has been proven in rats after a heart attack and in mice with some of the heart damage associated with diabetes. But because these studies are often based on findings in a lab or in animals, not in humans, we cannot yet be confident that CBD will benefit the human heart.
Since 2016, any CBD product that is presented as having medicinal value must be licensed and regulated as a medicine, regardless of whether it is actually effective. Manufacturers must follow very specific and robust rules around production, packaging and the information provided.
“It’s clear that CBD has potential,” says Professor Sumnall, “but we’re at a very early stage of that research.”
Many of these can be easily picked up from reputable high street stores, such as Holland & Barrett or Boots.
Harry Sumnall, Professor in Substance Use at Liverpool John Moores University, says: “In terms of the products found in shops, there’s virtually no evidence to support the claims made for a lot of them. There’s a lot of marketing that says CBD is a ‘miracle of the modern age’; however, the marketing has actually overtaken the evidence of what it’s effective for.”
“In terms of the products found in shops, there’s virtually no evidence to support the claims made for a lot of them.” Harry Sumnall, Professor in Substance Use at Liverpool John Moores University.
What is CBD used for?
CBD’s popularity has been given a boost by the fact that two CBD-containing medicines have been approved for prescription use by the NHS in England: Epidyolex, which has been found to reduce the number of seizures in children with severe epilepsy, and Sativex, which contains a mixture of CBD and THC, and is licensed for treatment of muscle stiffness and spasms in people with MS.
The biggest difference between CBD used in clinical trials and in stores is the dose. Research has shown that some products contain very little CBD (or even none at all). Others contain THC or other illegal drugs, or even alcohol instead of CBD. By contrast, in clinical trials the CBD is purified, manufactured to a very high standard and given at a much higher dose. It is also taken regularly and under medical supervision.
However, it also notes that this research is still in the early stages, and that more studies are needed before conclusions can be drawn on whether CBD is effective.
Harry Sumnall is a Professor in Substance Use at the Public Health Institute, Liverpool John Moores University. He was a member of the UK Government’s Advisory Council on the Misuse of Drugs between 2011 and 2019.
What is CBD, and is it legal in the UK?
EHRA 2021 is the online annual congress of the European Heart Rhythm Association (EHRA) of the European Society of Cardiology (ESC).
Marijuana or cannabis is the most commonly used psychoactive substance worldwide. 2 However, there is limited knowledge about safety of the drug in people with cardiac arrhythmias. This study examined the burden of arrhythmias in drug users admitted to hospital. It also compared length of hospital stay and deaths in hospital between those with and without an arrhythmia.
The researchers compared deaths between the two groups after adjusting for factors that could influence the relationship including age, sex, race, income, diabetes, heart failure, chronic kidney disease, obesity, and hospital location. Cannabis users with an arrhythmia had a 4.5 times higher odds of in-hospital mortality compared to those without an arrhythmia. Patients with an arrhythmia had a longer length of hospital stay (5.7 days) compared to those without (5.1 days).
Patients in arrhythmia group were older: the average age was 50.5 years compared to 38.3 years for those without an arrhythmia. Those with arrhythmias also had more co-existing health conditions.
Notes to editor.
The European Heart Rhythm Association (EHRA) is a branch of the European Society of Cardiology (ESC). Its aim is to improve patients’ quality of life and reduce sudden cardiac death by limiting the impact of heart rhythm disturbances.
1 Abstract title: Burden of arrhythmia in hospitalized patients with cannabis use related disorders: analysis of 2016-2018 national inpatient sample.
Sophia Antipolis – 23 April 2021 : A study of 2.4 million hospitalised cannabis users has found that those with an arrhythmia were 4.5 times more likely to die while in hospital than those without. The research is presented at EHRA 2021, an online scientific congress of the European Society of Cardiology (ESC). 1.
“People should be aware of this devastating outcome and be careful when using cannabis if they have a concomitant heart problem,” said study author Dr. Sittinun Thangjui of Bassett Healthcare Network, Cooperstown, US.
2 United Nations Office on Drugs and Crime. World Drug Report 2018.
References and notes.
The ESC brings together health care professionals from more than 150 countries, working to advance cardiovascular medicine and help people to live longer, healthier lives.
The study was conducted using the National Inpatient Sample database, which covers 97% of the US population. The study included 2,457,544 adult cannabis users admitted to hospital in 2016 to 2018. Of those, 187,825 (7.6%) patients had an arrhythmia. Atrial fibrillation was the most common, followed by abnormally slow heart rate and abnormally fast heart rate.
ESC Press Office Tel: +33 (0) 7 8531 2036 Email: [email protected]
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Dr. Thangjui said: “Our study highlights that heart rhythm disorders may be a warning sign for an increased risk of death in people who use cannabis. More studies are needed to confirm our results. In the meantime, it seems sensible to screen these patients for arrhythmias if they present to hospital so that those with a heart rhythm problem can be closely monitored.”
Information for journalists about registration for EHRA 2021.