cbd hemp oil and alsDecember 15, 2021
About Kalapa Clinic.
Amyotrophic Lateral Sclerosis, more commonly known as ALS or motor neurone disease, is a neurodegenerative disease that causes the depletion of the motor neurons in the body, i.e the neurons that are responsible for muscle movement. Although the average life expectancy is around 2-5 years after the initial diagnosis, (this is not the case for everyone look at Steven Hawkins for example!), several studies have shown that CBD can help to relieve some symptoms of ALS .
Many people around the world were unaware of what ALS was until 2015. A Facebook campaign called the ‘ice bucket challenge’ was recently launched to raise awareness of the disease. People all over the world including celebrities were having buckets of ice cold water thrown over them, to symbolise the feeling of the dying nerve endings that ALS sufferers have to endure on a daily basis . The campaign quickly became viral and has been one of the most successful in Facebook history, raising more than 100 million dollars and leading to the discovery of some ground breaking research.
Despite this breakthrough there are still millions of people around the world that are suffering from this disease. The main symptoms of ALS include:
A study undertaken at the Complutense University in Madrid showed the effects of CBD in mice with ALS. The mice were administered small doses of CBD and the effects were monitored for a short period of time. They found that due to the CBD the progression of the disease in fact slowed down, extending the life expectancy of the mice by 6 days on average. This time frame was translated into three years for humans.
Symptoms of ALS.
CBD or cannabidiol has been known to ease severe pains and can bring some relief to the symptoms of ALS:
Información creada y revisada por expertos en Cannabis Medicinal. Todas las publicaciones se basan en investigaciones médicas y con referencias clínicas.
Did you like the post? Give us some feedback! This post has been done based on existent research to the date of publication of the article. Due to the increase in studies based on medical cannabis, the information provided can vary over time and we’ll keep informing in further writings.
In some places, patients with ALS can apply through a medical marijuana program to receive oils, tinctures, concentrates, or raw cannabis buds that contain high levels of both CBD and THC. The current research to date suggests this is the best option for ALS sufferers.
Eventually, as these motor neurons are destroyed, those affected are no longer able to walk, talk, eat, or drink. The disease ultimately becomes fatal when the motor neurons controlling the lungs fail.
Both CBD and THC could offer support for the condition. Most of the case studies showing improvements in lifespan and symptoms were using marijuana containing both THC and CBD.
Updated on November 13, 2021.
A review of CBD and ALS was recently published  calling for more research in this area.
2. Familial ALS.
We recommend starting with a low dose and building up gradually by adding 2 mg to 5 mg of CBD each day. Once symptoms are alleviated, you’ve found the right dose. According to case reports, CBD can relieve symptoms such as insomnia, pain, and muscle tremors almost immediately, while the longevity-enhancing effects of the compound would take much longer and won’t be as noticeable. Further research would be needed to confirm these kinds of effects.
There are medications available that may slow neuronal cell death and improve daily functioning. But the majority of treatment is purely supportive — addressing significant symptoms and providing increased levels of support as those affected lose their ability to walk, talk, and take care of themselves.
These conditions are independent of each other but have similar underlying mechanisms.
It’s clear that more research is needed to investigate the effects of CBD on ALS in human subjects. However, the research we do have is very promising.
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder affecting the nerves responsible for muscle control.
An animal study published in 2004 investigated the role of THC — the primary psychoactive cannabinoid in the cannabis plant — on mice with ALS to measure any changes . The results of this study reported that the mice who were given THC had significantly less severity with their symptoms than mice not given the THC treatments.
Other treatments for ALS include:
CBD may be useful for a range of other neurodegenerative disorders, including Alzheimer’s disease , Parkinson’s disease , and multiple sclerosis . Current CBD research related to these conditions is limited, but promising enough to be looked into further.
Unfortunately, there are no clinical studies investigating the effects of CBD for ALS sufferers, despite years of case studies and promising research on related neurological disorders. However, there are a lot of case studies showing positive anecdotal impacts with both legal and illegal cannabis and CBD use .
Because there are no good clinical trials involving CBD for ALS, there are no specific dosages identified nor characteristic results to be expected. However, studies involving CBD and other neurodegenerative disorders often report that high dosages are needed to receive benefits. Therefore, it’s likely to assume that the dose for ALS is also higher than average.
Tips to Getting the Most Out of Your CBD.
Therefore, we recommend opting for a full-spectrum CBD oil rather than a purified CBD extract with all other cannabinoids and terpenes removed. But depending on where you live, you may or may not have access to CBD products that contain THC in concentrations higher than about 0.3%.
However, as with any neurodegenerative disorder, it’s wise to speak with your physician before trying CBD or marijuana products for ALS symptoms because, in rare cases, CBD oils may have a negative interaction with other medication you might be taking, and you may also require liver enzyme monitoring . Therefore, it’s better to ask your doctor before assuming it’s 100% safe.
Therefore, for best results, it’s recommended that you aim for the high-strength dose of CBD, and take this dose consistently over the long term.
The study highlighted a list of hypothetical benefits CBD is believed to offer ALS patients, including:
Stephen Hawking had the condition for most of his life but ultimately passed away at the age of 76.
No cure exists for this condition.
The disease involves gradual muscle paralysis as the neurons controlling the muscles break down. We each have millions of specialized nerve cells — called motor neurons — tasked with transmitting messages from the brain to the muscles and back again.
Another Manifestation of ALS: Bulbar ALS.
CBD produces well-known anti-inflammatory, antispasmodic, neuroprotective, and antioxidant effects within the body. It’s through these effects that CBD is, therefore, thought to be useful for a spectrum of neurological disorders — including ALS.
There is no cure for ALS but there are a few treatments available, such as FDA-approved riluzole and edaravone. Riluzole, a glutamatergic neurotransmission inhibitor, does not provide relief from the symptoms of ALS, but it can extend life expectancy by two to three months. Edaravone, an antioxidant drug, can slow the decline of daily functions and halt the progression of ALS. CBD interacts with some medications, so always check with your doctor before using it.
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However, if you’re unable to get any hemp or marijuana products that contain THC, that’s okay. CBD is still likely to be effective for this condition and is generally better for relieving muscle tremors, insomnia, and anxiety than products containing THC.
This form of ALS can affect anybody — regardless of their gender, ethnicity, or age. However, it is more common in men, caucasian people, and persons older than 60 years, with peak onset around 58 to 63 years.
Amyotrophic lateral sclerosis, or ALS, is also referred to as Lou Gehrig’s Disease because of the famous baseball player who was forced to retire from the sport in 1939 after being diagnosed with the condition.
Additionally, there is a growing body of evidence to suggest that THC is also beneficial for ALS.
Familial ALS is an inherited form of the disease. It accounts for 5% to 10% of cases. Peak age at onset is 47 to 52 years.