cbd oil for aspergersDecember 15, 2021
Some studies have attempted to expand on these theories by studying ‘rat models’ of autism. The results generally show a significant improvement in socializing behavior in the rats that have consumed CBD.
CBD is non-psychoactive and non-addictive, and it is impossible to consume an overdose.
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6. Treating Psychological Conditions.
Consuming CBD oil in the form of a gummy, capsule, or CBD-infused food could also be beneficial. However, as it has to go through the digestive system before entering the bloodstream, it will take much longer to kick in compared with sublingual consumption or vaping. This makes it a good option for.
According to research, CBD also modulates the production of GABA (gamma-aminobutyric acid), an amino acid that acts as a neurotransmitter responsible for relaxation. GABA slows the heart rate and lowers blood pressure in response to mental overstimulation, essentially helping the mind (and body) to de-stress.
It’s normally best to buy CBD online. That way, you can easily compare different brands, potencies, and flavors at your leisure, without any pressure to buy. But you need to ensure that you’re buying a top-quality product from a reputable company.
Although more scientific evidence is needed, CBD is becoming an increasingly popular supplement for people with Asperger syndrome.
Clinical trials have shown that CBD can potentially be used to reduce hyperactivity of the serotonin receptors and has similar effects to lithium, which is a common pharmaceutical mood-stabilizing medication. It has also been shown to be an effective treatment for people with psychosis disorders such as schizophrenia.
Many of these conditions are influenced in some way by serotonin activity in the brain.
Luckily, it’s impossible to overdose on CBD, so there’s no need to worry about doing any serious harm. Even so, you still want to avoid experiencing any unwanted (albeit mild) side-effects, such as nausea, dry mouth, or drowsiness.
1. Boosting Anandamide Production.
Although there is little clinical research into the effects of CBD on people with autism and Asperger syndrome, there are considerations through the reports of doctors as well as families who are monitoring someone taking CBD to help manage the condition. It would seem, so far, that this anecdotal evidence is positive.
Livvy is a registered nurse (RN) and board-certified nurse midwife (CNM) in the state of New Jersey. After giving birth to her newborn daughter, Livvy stepped down from her full-time position at the Children’s Hospital of New Jersey. This gave her the opportunity to spend more time writing articles on all topics related to pregnancy and prenatal care.
Furthermore, THC has been shown in studies to be particularly detrimental to people suffering from psychosis and similar psychological conditions. As these can often go hand in hand with Asperger syndrome, it’s important to ensure it is not consumed.
With the right support in place, people with Asperger syndrome are perfectly capable of living a fulfilling and productive life.
Obviously, this option is only for adults – children should not be vaping anything. But vaping offers the same benefits as sublingual consumption, as the CBD is able to bypass the digestive and metabolizing systems by entering the bloodstream directly through the lungs. Again, this is great for managing symptoms quickly and at short notice.
CBD is by no means a one-size-fits-all treatment for Asperger syndrome, and it’s certainly not a cure. And although there are many potential benefits for including it in the management of the condition, as outline above, there are some cautions to bear in mind.
Additionally, research suggests that CBD positively interacts with the anterior cingulate cortex (ACC). This is a part of the brain that plays a key role in the integration of cognitive information (including emotions). This, therefore, makes it effective at treating anxiety- and stress-related disorders.
The laboratories are in no way associated or affiliated with the companies or brands they’re testing, so they have no reason to be anything other than upfront about their findings. Plus, these labs have consistent outstanding reputations to uphold — and there’s no way they’re going to put that at risk by approving a dodgy batch.
The CoA should always indicate the potency, purity, and overall quality and contents of the CBD product, including the exact level of THC.
A lack of social skills is perhaps one of the most commonly associated ‘symptoms’ of Asperger syndrome. People with the condition offer experience mild to severe cases of social anxiety and disfunction, inability to communicated effectively, and inability to read and respond to generally recognized social cues.
Lastly, remember that it’s always advisable to consult a medical professional before taking any new supplement as a treatment for a condition.
Blocking the CB1 receptor can relieve seizures and memory issues in a mouse model of fragile X syndrome, a condition related to autism, according to a 2013 study in Nature Medicine 6 . A 2018 clinical trial of a synthetic CBD drug by the drug maker Zynerba showed significant improvements in anxiety and other behavioral traits in people with fragile X. Cannabinoid receptor activation has also been shown to lead to memory improvements in fragile X mice 7 .
In 33 states, along with the District of Columbia and Puerto Rico, however, people can legally buy and use medical cannabis for certain approved conditions, such as seizures and sleep problems, although the list of qualifying conditions varies by state. These same states, plus 13 others, also allow CBD oil. Fourteen states plus Puerto Rico have approved medical marijuana for autism, and some additional states may allow it for autistic people at a doctor’s discretion.
Cannabis may have effects that go beyond the cannabinoid receptors, too. Mice that ingested CBD over extended periods of time displayed changes to DNA methylation in sections of the genome associated with autism, a 2020 study showed 10 . The researchers suggested that epigenetic changes may be at least partly responsible for CBD’s behavioral effects, though they did not directly examine the mice’s behavior.
How might cannabis help autistic people? Epidiolex’s success has spurred many parents to try marijuana and cannabis extracts for seizures, behavioral issues and other autism-related traits in their children, but experts warn that these drugs remain largely untested for such purposes. Some studies on cannabinoids have shown promising results in animal models and in early-stage clinical trials, but this research does not yet support their widespread use.
GW Pharmaceuticals, the company that makes Epidiolex, is conducting a trial of the drug for Rett syndrome, a neurodevelopmental condition related to autism. The Rett syndrome trial is not focused on alleviating seizures, but on improving cognitive and behavioral problems. The company is also recruiting autistic children and teenagers for a phase 2 trial of cannabidivarin, another component of cannabis. That trial will examine cannabidivarin’s effect on a range of traits in autistic children, including repetitive behaviors, and on quality of life.
CBD is considered minimally psychoactive, but many preparations of it contain undisclosed amounts of THC, which may lead to inadvertent intoxication and impairment.
Are some cannabis products safer or more effective than others? Many people who self-administer cannabinoids for epilepsy or other conditions cultivate it at home. Others purchase it directly from companies rather than buying it at state-licensed dispensaries, and research has shown that these products are not created equal.
What is medical marijuana? Medical marijuana generally refers to any product derived from cannabis plants — including dried flowers, resins and oils — that has been recommended by a doctor. It may be consumed directly or infused into an array of foods, lozenges and candies. These products have become popular among autistic people and their families for treating a broad swath of conditions, including insomnia, epilepsy and chronic pain.
Are there any cannabis -derived drugs approved to treat autism or related conditions? To date, the U.S. Food and Drug Administration has approved only one cannabis-derived drug: Epidiolex. It is a liquid cannabis extract containing purified CBD that can decrease seizures in people with Dravet syndrome or Lennox-Gastaut syndrome — severe forms of epilepsy that are sometimes accompanied by autism — and in those with tuberous sclerosis complex. It is available only by prescription, and only for these three conditions.
In many states where medical marijuana is legal, licensed dispensaries sell products that have been tested by accredited laboratories to verify the presence of active ingredients and the absence of contaminants. Some states permit individuals or their licensed caregivers to grow their own cannabis plants for personal use. Most states in the U.S. require people who use medical marijuana to register and get a special identification card.
Is medical marijuana legal ? Yes and no. Federal law in the United States classifies marijuana and its derivatives as ‘Schedule 1’ drugs, meaning that they have no accepted medical use and a high potential for abuse. Schedule 1 drugs are illegal, and research on them requires labs to follow strict security protocols and adhere to regular facility inspections.
Depending on the strain of the plant and the processing methods used, these products contain varying levels of active ingredients, including tetrahydrocannabinol (THC) — responsible for the ‘high’ associated with marijuana — and cannabidiol (CBD), which is minimally psychoactive. Much of the research on medical applications focuses on CBD. There are also more than 500 other compounds in marijuana that may affect people’s behavior and cognition 1 .
The actual potency of CBD products varies widely from their advertised concentrations, according to a 2017 study in JAMA , and some products contain more than the legal limit of THC — potentially enough to cause intoxication, especially in children 12 . Less than one-third of the products tested contained within 10 percent of the advertised CBD concentration, and THC was detected in about 21 percent of samples.
Cannabis’ active ingredients are thought to exert their effects by binding to proteins called cannabinoid receptors in the brain: THC activates the CB1 and CB2 receptors, whereas CBD seems to block them 2 .
Research has also demonstrated that CBD alleviates seizures in children with CDKL5 deficiency disorder, an autism-linked condition that is characterized by seizures and developmental delay. CBD also lessens seizures and improves learning and sociability in a mouse model of CDKL5 deficiency disorder.
Some research has shown that recreational marijuana use beginning in one’s teenage years can have negative long-term effects on cognition 11 . But experts note that the dosages used for medical purposes are often quite lower than those used in a recreational context.
Complicating the picture, CBD alone may not be sufficient for cannabis’ therapeutic effects. A 20-to-1 ratio of CBD to THC relieves aggressive outbursts in autistic children, a 2018 study suggests 8 . This same ratio of compounds significantly improved quality of life for some children and teenagers with autism in a 2019 study 9 . Specifically, researchers observed significantly fewer seizures, tics, depression, restlessness and outbursts. Most participants reported improvements, and about 25 percent of participants experienced side effects such as restlessness.
Many studies have shown that cannabis treatment carries only minor side effects such as sedation or restlessness, but these studies have not looked at long-term side effects. Researchers still don’t have a solid grasp on how the active ingredients in marijuana actually affect the brain, nor do they know how these compounds might impact a child or teenager’s developing brain or interact with other medications.
Both types of cannabinoid receptors are located in neurons in the brain and throughout the body. The brain contains more CB1 than CB2 receptors, and the activation of each receptor type affects a range of ion channels and proteins involved in cell signaling 3 . The ultimate effects of cannabinoid receptor activation depend on which body system they belong to. For instance, the activation of CB1 receptors in the brain can either increase or decrease neuron excitability, depending on which kind of neuron a cannabinoid binds to; activation of CB2 receptors in the digestive system can decrease inflammation 4,5 .
Under U.S. federal law, CBD products manufactured from industrial hemp are legal as long as they contain no more than 0.3 percent THC. And in some states, CBD oil is permitted to contain up to 5 percent THC.
Over the past decade, autistic people and their families have increasingly experimented with medical marijuana and products derived from it. Many hope these compounds will alleviate a range of autism-related traits and problems. But scientists are still in the early stages of rigorous research into marijuana’s safety and effectiveness, which means that people who pursue it as treatment must rely mostly on anecdotal information from friends and message boards for guidance.
Here we explain what researchers know about the safety and effectiveness of cannabis for autism and related conditions.
Based on the clinical trials of Epidiolex, the FDA warns that the drug could cause elevated liver enzymes, which can be a sign of liver damage. This is especially likely in people who take Epidiolex and the epilepsy drug valproate at the same time.
In many European countries, as well as in Australia, Canada, Israel and Jamaica, medical cannabis is legal, with specific laws varying from country to country.
Is cannabis safe? It’s unclear. Large doses are usually not fatal, but taking it regularly may have long-term effects.
In a presentation at the 2020 meeting of the American Academy of Neurology, researchers concluded that ‘artisanal’ CBD products available for purchase online and in health-food stores are not as effective at controlling seizures as pharmaceutical-grade CBD.
While CBD is legal in the United States, the Federal laws  get murky when it comes to CBD. CBD is federally legal, as long as it is not being infused in food or labeled as a dietary supplement.
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Cannabidiol (CBD) is one component of cannabis or marijuana. Whole cannabis or marijuana contains many other compounds, including THC, the compound credited for the euphoric high feeling. Cannabis oil is extracted from marijuana to make a wide range of non-intoxicating medical products.
Third-party testing means that the CBD manufacturer sends a sample of their product to a lab to be tested for cannabinoid and terpene profiles, heavy metals, solvents, and biological contaminants.
Over the past decade, there has been an increase in anecdotal evidence  showing that CBD, or cannabidiol, can help with seizures, insomnia, sensory issues, stress, social anxiety, depression, and other behavioral issues that people with Asperger Syndrome may have.
Legal medical cannabis in the US is still fairly new, so it has been difficult to approve or fund studies until recently. While CBD is legal in all 50 states, federal law still classifies marijuana (even medical marijuana) and its derivatives as illegal.
Delivery method matters.
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In CBD oil, concentrate refers to the levels of CBD found in a product compared with other compounds. They are highly potent and condensed. The benefit of a concentrate is that you can get a large dose of CBD that will begin acting quickly.
More clinical trials are needed to show the effects of medical marijuana and related cannabis products on Asperger Syndrome.
When selecting a CBD for Aspergers, you want to make sure you select a reputable company that uses high-quality ingredients and that submits all products for third-party testing for quality and purity. Other factors to consider are CBD products with less than .3% THC, full-spectrum or isolate, CBD concentrate, and dosage.
Endocannabinoids and their receptors are found throughout the body and are believed to affect behavior in many ways. In people with Asperger syndrome and ASD, there is a deficiency or imbalance in their endocannabinoid system.
CBD can help restore balance in the endocannabinoid system of people with Asperger’s and autism spectrum disorders. It can alleviate autism symptoms such as seizures, insomnia, sensory issues, stress, anxiety, depression, and other behavioral issues that people with Asperger Syndrome may have.
No. While it may help you feel more relaxed or less anxious, you will not experience the euphoric, intoxicated, or “high” sensation as from whole cannabis or marijuana. CBD oil does not contain Tetrahydrocannabinol or THC, the psychoactive compound found in cannabis.
The article is checked by our editorial team, which includes registered dietitians and medical doctors with extensive, real-world clinical experience.
Third-party testing is a crucial indicator of quality and purity, as long as the results are made available to customers. It is not enough for a manufacturer to say that they use third-party testing. They must show what it is that they test for and the results for those tests.