cbd products for pain

December 15, 2021 By admin Off

CBD may help to reduce pain by acting on a variety of biological processes in the body. CBD has been shown to work as an anti-inflammatory, antioxidant, and analgesic. CBD may also reduce the anxiety that people living with chronic pain often experience.

The CBD compound itself is still classified as Schedule I drug (along with LSD and heroin). Federally, CBD derived from non-hemp marijuana is illegal. If you live in a state that has legalized marijuana, you can find non-hemp derived CBD products at a medical marijuana dispensary.

Importantly, CBD is hydrophobic and lipophilic , meaning it will dissolve in fats. The dissolution helps it to be carried across the blood-brain barrier and affect your CNS, where it can have a broad range of positive effects on pain including:

10. O’Sullivan SE. An update on PPAR activation by cannabinoids. Br J Pharmacol. 2016;173(12):1899–1910.

13. Nuutinen T. Medicinal properties of terpenes found in Cannabis sativa and Humulus lupulus. Eur J Med Chem . 2018;157(5):198-228.

WHAT CAN I DO RIGHT NOW ?

7. De Gregorio D, McLaughlin R, Posa L, et al.Cannabidiol modulates serotonergic transmission and reverses both allodynia and anxiety-like behavior in a model of neuropathic pain. Pain. 2019;160(1):136-150.

But it is important to be cautious if you are taking other medications or substances, like alcohol. Specifically:

There is no one best CBD oil for pain. The type will depend on your pain condition, how you consume the CBD, and your body chemistry. An important consideration will be whether the oil is a CBD isolate, a full spectrum extract, or a broad spectrum extract. It is also important to know you are buying a trustworthy product, especially because the CBD market is not regulated.

You can vape a full spectrum CBD, which may get you a bit high, even when using a strain with trace amounts of THC.

CBD itself does not bind to receptors but is thought to work by inducing other components of the cannabinoid system.

CBD is thought to be helpful in easing the symptoms of the following conditions.

First, consider the source. Studies show that continuous CBD consumption is generally safe and can have many benefits. However, because of CBD’s complicated status, the compound itself may still be classified as an illegal substance. See the FDA’s FAQs on cannabis regulations (#9).

Let’s break it down:

Ingesting CBD can be more beneficial for people with systemic inflammatory conditions (such as rheumatoid arthritis or Multiple Sclerosis [MS]), autoimmune conditions, and full body pain, caused by neurological conditions such as fibromyalgia or cancer pain.

A budtender – that’s what they call dispensary pharmacists – or your doctor can guide you, but here’s a quick overview.

Just How Legal is CBD?

Yes, cannabidiol (CBD) does come from marijuana. But let’s say it again and louder for the people in the back: No, it does not get you high! In the United States, legal CBD products are predominantly derived from the hemp plant, which is a species of the sativa marijuana plant. A key difference is that hemp contains 0.3% or less of THC cannabinoids.

9. Nicholson AN, Turner C, et al. Effect of Delta-9-tetrahydrocannabinol and cannabidiol on nocturnal sleep and early-morning behavior in young adults. J Clin Pshychopharmacol. 2004;23(3):305-313.

Your Natural Endocannabinoid System Supports CBD.

Vaping has become a popular form of taking CBD. Unlike rolling a joint, vaping involves a CBD oil cartridge that is inserted into a vaping pen. While some may assume that vaping is safer than smoking, there are dangers associated with both practices regarding lung health.

1. Corroon J, Phillips JA. A cross-sectional study of cannabidiol users. Cannabis Cannabinoid Res. 2018;3(1):152-161.

Because of the way the endocannabinoid system works, the bioavailability of CBD is an important factor in how you will respond . Bioavailability is the amount of a substance that successfully makes it into the bloodstream and has an effect. Think about how some medications require you to take them with food or water, or on an empty stomach. Well, the amount of CBD that you actually absorb when taking a CBD product works the same way and will depend on:

8. Atalay S, Jarocka-Karpowicz I, Skrzydlewska E. Antioxidative and Anti-Inflammatory Properties of Cannabidiol. Antioxidants . 2020;9(1):21.

CBD’s Potential Benefits.

5. Yamaoka G, et al. Different analgesic effects of adenosine between postoperative and neuropathic pain. J Orthop Sci. 2013;18(1):130-136.

Our natural endocannabinoids function on demand, meaning that when our body senses inflammation, or needs to return to homeostasis (a state of stable balance) it will release endocannabinoids that bind to cannabinoid receptors.

Selecting a CBD product depends on:

You can also vape a CBD isolate or broad spectrum oil, which should not induce a high.

Our body’s endocannabinoid system is composed of three main components:

How do you know you are getting the CBD the package claims? You don’t, but there are a few ways to put the odds in your favor.

That depends on how you take your CBD oil. The most predictable consumption method is sublingual (under the tongue) using a spray or tincture. According to the American Arthritis Foundation, 16 effects are usually felt within 15 to 45 minutes.

The 2018 US Farm Bill legalized the growing of hemp and sale of hemp-derived products, which made CBD legal at the federal level (mostly). As noted, hemp is a species of the marijuana plant with one very important distinction: the variety must have less than 0.3% THC. So, if the CBD you buy comes from a hemp plant with less than 0.3% CBD and is grown in accordance with the 2018 Farm Bill regulations, and you live in a state where CBD is legal, you are in full abidance of the law.

CBD oil can be taken as drops under the tongue or as a capsule, and it can also be applied directly to the skin in topical form. Sublingual drops typically take 30 minutes to start working while it may take up to two hours to feel the effects of capsules, gummies, and topicals. 

NuLeaf Naturals’s full-spectrum formula is made with organic hemp grown in Colorado and organic virgin hemp seed oil. The brand uses a unique CO2 extraction method that creates a potent blend of terpenes, cannabinoids, essential oils, and phytonutrients, which is meant to enhance a product’s wellness benefits, including pain relief. This CBD oil is easy to use because it offers a consistent strength, 30 milligrams per serving, no matter the size of the bottle.

Before purchasing a CBD oil, read the full ingredient list to check for compounds or carrier oils that could cause an allergic reaction. Choosing CBD products that use all-natural flavorings with zero additives may decrease the risk of side effects.

Available in a variety of strengths and flavors, cbdMD’s broad-spectrum formula is a great choice for individuals who are new to CBD. The product is vegan and gluten-free, and the brand offers a 60-day money-back guarantee if you’re not satisfied with the oil. The fact that it uses U.S.-grown hemp ensures that strict safety standards are met during the production process.

The amount of CBD you should take depends on a number of different factors, including your height, weight, and whether or not you've used CBD oil before. Consult a doctor about proper doses if you're planning to use a product for pain management.

Additional ingredients.

CBD oil is often used to relax the mind, but did you know that some individuals with chronic pain and joint conditions like arthritis also take it? If you're looking for relief, keep reading to learn more about how CBD can help ease your pain.

According to primary care physician Carrie Lam, MD, who specializes in functional and integrative medicine at the Lam Clinic in Tustin, California, a variety of studies have been performed on the benefits of cannabis for pain. "Some of the disorders cannabis can help with include arthritis, fibromyalgia, endometriosis, neuropathy—resulting from nerve damage—cancer, [and] emotional pain," she states. The benefits of cannabis, and CBD, for pain are believed to result from its anti-inflammatory properties.

Potency: 60 milligrams of CBD per 1 milliliter serving in 30- and 100-milliliter bottles.

Medterra’s broad-spectrum formula is 99% CBD oil and 1% organic MCT oil. The hemp is organically grown in Kentucky where it then goes through a CO2 extraction process to preserve the pure blend of phytonutrients, cannabinoids, and terpenes found in the hemp plant.

Meg Byrne, DC, chiropractor and certified acupuncturist with Acacia Natural Medicine in Scottsdale, Arizona—and the Spring Training chiropractor for the San Diego Padres—explains the central role that terpenes found in CBD oil may play in pain relief. "Terpenes, specifically, affect the CB1 and CB2 receptors and neurotransmitters of the brain," she notes. The most common therapeutic terpenes include myrcene, caryophyllene, terpineol, and linalool. 

Potency: 80 milligrams of CBD per 1 milliliter serving.

Choosing a CBD oil for pain relief involves more than just picking a flavor or potency. Here are a few things to consider when shopping for a CBD product.

This full-spectrum CBD oil from Green Roads is vegan and gluten-free, plus it comes in three different strengths—mild, moderate, and mighty. The formula has no artificial flavors or colors, and the hemp used is farmed in the U.S. The dropper features an easy-to-use measuring system and each box has a QR code that links directly to the independent lab results for that specific product.

"When these terpene-rich oils are blended with CBD isolate, research supports the use of topical and ingested CBD for chronic pain," adds Byrne. "Patients are seeing a decrease in pain associated with osteoarthritis, muscle injuries, rheumatoid arthritis, and tendonitis."

Plant People offers its USDA organic CBD oil in three potencies, making it easier to find the right dose. The brand recommends using this product to help reduce cramps deep within your muscles and ease joint tension for increased mobility. As a bonus, the formula includes turmeric, ginger, and black pepper, which provide anti-inflammatory benefits. It’s also vegan, non-GMO, gluten-free, and keto-friendly as well as Current Good Manufacturing Practice (cGMP) certified for potency and purity.

Best Overall: Spruce Extra Strength Lab Grade CBD Oil.

CBDistillery Relief + Relax tinctures come in a variety of concentrations to provide pain relief support for both novice and experienced CBD users. This formula is certified by the U.S. Hemp Authority, and all products are made with non-GMO industrial hemp that’s grown using natural farming practices.

The purity and potency of a CBD product can be checked through third-party lab testing. Look for the following labels on a brand's website:

Potency: 10, 25, and 50 milligrams of CBD per 1 milliliter servings.

Potency: 17, 33, 83, and 167 milligrams of CBD per 1 milliliter servings.

More research needs to be conducted to confirm whether CBD alone can help reduce or manage pain. Most of the current research looks at treatments containing both tetrahydrocannabinol (THC) and CBD, so it's unclear which compound is providing the most wellness benefits.

This formula from Charlotte’s Web is made using CO2 extraction and contains full-spectrum, Colorado-grown hemp. The environmentally friendly process creates a pure and potent CBD oil that’s chock-full of beneficial compounds. The brand says the product is designed to reduce exercise-induced inflammation, and it comes in three delicious flavors—mint chocolate, orange blossom, and lemon twist.

Potency: 10, 25, 50, 100, 166.5, and 250 milligrams of CBD per 1 milliliter servings.

Third-party lab testing.

This list of the best CBD oils for pain relief was compiled based on personal experiences with the products, customer reviews, and in-depth research into hemp sources, potency, price, and third-party lab testing. All of the oils we recommend are high-quality and meet strict purity and safety standards.

A study of 29 patients with peripheral neuropathy (weakness, numbness, and pain from nerve damage) in their lower extremities found that topical CBD provided a "statistically significant reduction" in pain over a placebo. In contrast, a 2020 review of research on CBD's connection to pain, also published in Frontiers in Pharmacology , found that in "studies of generalized chronic pain, CBD treatment did not significantly reduce measures of pain." The authors did note, however, that "there was consistent improvement in patient-reported quality of life and quality of sleep." If this is an avenue you're interested in exploring, talk to your primary care physician before making any changes to your pain management regimen.

"Some of the anti-inflammatory effects are the result of the interaction of cannabis components with CB2 receptors in the brain," explains Dr. Lam. "If activated, the receptors release fewer pro-inflammatory substances called cytokines—which means less inflammation."

Potency: 80 milligrams of CBD per 1 milliliter serving.

The best CBD oils use hemp sources from the U.S. that were grown through organic farming practices. Unlike CBD oil manufactured overseas, the U.S. requires federal testing to ensure the hemp is pure, potent, and safe to use and consume. A product's potency is typically measured by milligrams of CBD per 1 milliliter serving. The oils featured in this article have higher potencies than the ones you might use for stress relief.

CBD is not meant to be a cure for pain or chronic pain conditions. Talk to a health care professional before trying a CBD product for pain and do not stop taking prescription medication unless directed by your doctor.

Potency: 12, 24, and 48 milligrams of CBD per 1 milliliter servings.

This 100% natural CBD oil by Spruce is an extra-potent formula that may provide some comfort for individuals looking to manage chronic pain. It’s organic, vegan, gluten-free, pesticide-free, and contains no artificial flavors, sweeteners, and preservatives, plus it’s made in the U.S. The full-spectrum oil undergoes third-party testing to ensure proper levels of THC and potency for pain relief support.

The Farm Bill removed all hemp-derived products, including CBD, from the Controlled Substances Act, which criminalizes the possession of drugs. In essence, this means that CBD is legal if it comes from hemp, but not if it comes from cannabis (marijuana) – even though it is the exact same molecule. Currently, many people obtain CBD online without a medical marijuana license, which is legal in most states.

Some CBD manufacturers have come under government scrutiny for wild, indefensible claims, such that CBD is a cure-all for cancer or COVID-19, which it is not. We need more research but CBD may prove to be a helpful, relatively non-toxic option for managing anxiety, insomnia, and chronic pain. Without sufficient high-quality evidence in human studies, we can’t pinpoint effective doses, and because CBD currently is typically available as an unregulated supplement, it’s hard to know exactly what you are getting.

CBD, or cannabidiol, is the second most prevalent active ingredient in cannabis (marijuana). While CBD is an essential component of medical marijuana, it is derived directly from the hemp plant, a cousin of marijuana, or manufactured in a laboratory. One of hundreds of components in marijuana, CBD does not cause a “high” by itself. According to a report from the World Health Organization, “In humans, CBD exhibits no effects indicative of any abuse or dependence potential…. To date, there is no evidence of public health related problems associated with the use of pure CBD.”

Is cannabidiol legal?

Outside of the US, the prescription drug Sativex, which uses CBD as an active ingredient, is approved for muscle spasticity associated with multiple sclerosis and for cancer pain. Within the US, Epidiolex is approved for certain types of epilepsy and tuberous sclerosis.

CBD is readily obtainable in most parts of the United States, though its exact legal status has been in flux. All 50 states have laws legalizing CBD with varying degrees of restriction. In December 2015, the FDA eased the regulatory requirements to allow researchers to conduct CBD trials. In 2018, the Farm Bill made hemp legal in the United States, making it virtually impossible to keep CBD illegal – that would be like making oranges legal, but keeping orange juice illegal.

CBD comes in many forms, including oils, extracts, capsules, patches, vapes, and topical preparations for use on skin. If you’re hoping to reduce inflammation and relieve muscle and joint pain, a topical CBD-infused oil, lotion or cream – or even a bath bomb — may be the best option. Alternatively, a CBC patch or a tincture or spray designed to be placed under the tongue allows CBD to directly enter the bloodstream.

People taking high doses of CBD may show abnormalities in liver related blood tests. Many non-prescription drugs, such as acetaminophen (Tylenol), have this same effect. So, you should let your doctor know if you are regularly using CBD.

CBD has been touted for a wide variety of health issues, but the strongest scientific evidence is for its effectiveness in treating some of the cruelest childhood epilepsy syndromes, such as Dravet syndrome and Lennox-Gastaut syndrome (LGS), which typically don’t respond to antiseizure medications. In numerous studies, CBD was able to reduce the number of seizures, and, in some cases, stop them altogether. Epidiolex, which contains CBD, is the first cannabis-derived medicine approved by the FDA for these conditions.

Animal studies, and self-reports or research in humans, suggest CBD may also help with:

How can CBD be taken?

Side effects of CBD include nausea, fatigue and irritability. CBD can increase the level of blood thinning and other medicines in your blood by competing for the liver enzymes that break down these drugs. Grapefruit has a similar effect with certain medicines.

A significant safety concern with CBD is that it is primarily marketed and sold as a supplement, not a medication. Currently, the FDA does not regulate the safety and purity of dietary supplements. So, you cannot be sure that the product you buy has active ingredients at the dose listed on the label. In addition, the product may contain other unknown elements. We also don’t know the most effective therapeutic dose of CBD for any particular medical condition.

Cannabidiol (CBD) is often covered in the media, and you may see it touted as an add-in booster to your post-workout smoothie or morning coffee. You can even buy a CBD-infused sports bra. But what exactly is CBD? And why is it so popular?

If you decide to try CBD, make sure you are getting it from a reputable source. And talk with your doctor to make sure that it won’t affect any other medicines you take.

How is cannabidiol different from marijuana, cannabis and hemp?