cbd psychoactive effectsDecember 15, 2021
Cannabidiol (CBD) is a naturally occurring, non-psychotropic cannabinoid of the hemp plant Cannabis sativa L. and has been known to induce several physiological and pharmacological effects. While CBD is approved as a medicinal product subject to prescription, it is also widely sold over the counter (OTC) in the form of food supplements, cosmetics and electronic cigarette liquids. However, regulatory difficulties arise from its origin being a narcotic plant or its status as an unapproved novel food ingredient. Regarding the consumer safety of these OTC products, the question whether or not CBD might be degraded into psychotropic cannabinoids, most prominently tetrahydrocannabinol (THC), under in vivo conditions initiated an ongoing scientific debate. This feature review aims to summarize the current knowledge of CBD degradation processes, specifically the results of in vitro and in vivo studies. Additionally, the literature on psychotropic effects of cannabinoids was carefully studied with a focus on the degradants and metabolites of CBD, but data were found to be sparse. While the literature is contradictory, most studies suggest that CBD is not converted to psychotropic THC under in vivo conditions. Nevertheless, it is certain that CBD degrades to psychotropic products in acidic environments. Hence, the storage stability of commercial formulations requires more attention in the future.
Chemical structures of ( a…
Google trends analysis for cannabidiol…
Conflict of interest statement.
Chemical structures of ( a…
The authors declare no conflict of interest.
Overview of various chemical conversions…
Chemical structures of ( a…
Overview of various chemical conversions of cannabidiol (CBD) to different conversion products and…
Google trends analysis for cannabidiol (CBD) (Data source: Google Trends ).
Chemical structures of ( a ) cannabinol (CBN) including the numbering system, (…
Keywords: Cannabis sativa; cannabidiol; degradation; psychotropic effects; tetrahydrocannabinol.
Chemical structures of ( a ) hexahydrocannabinol (HHC), ( b ) cannabigerol (CBG)…
Chemical structures of ( a ) cannabidiolic acid (CBDA) and ( b )…
CBD is often used to alleviate symptoms associated with:
Although CBD in certain forms is legal in most states, the specifics of the legality of any THC or CBD product can vary from one state to the next. Several states have also approved the use of marijuana and THC for recreational purposes.
Like THC, CBD can also be consumed in a number of different forms. CBD oils can be formulated for vaping, although there have been recent concerns about the health dangers posed by vaping.
When choosing CBD products, it is also important to consider its formulation. Isolate products contain only CBD. Broad-spectrum products contain other cannabinoids with the exception of THC, while full-spectrum CBD products contain CBD, THC, and other cannabinoids.
While research on the potential health benefits of THC, CBD, and other cannabinoids is still in the early stages, there is evidence that these substances may be helpful for conditions including:
It is also important to remember that CBD and THC work in a number of different areas of the brain and researchers do not yet fully understand the effects that these cannabinoids have, either alone or in conjunction with one another.
One study found that CBD helped block some of the potential psychiatric effects of THC. The authors of the study suggest that such findings have important implications for the use of cannabis products. People who are prone to unwanted side effects, for example, may be able to still gain the potential health benefits by sticking to products that are low in THC and higher in CBD content.
Taking CBD along with THC has also been shown to help reduce some of the unwanted effects that THC may have. For example, one study suggests that CBD may potentially reduce some of the negative cognitive effects of regular cannabis use. For example, people who use cannabis, particularly when it has high THC levels, may have a greater risk of experiencing psychiatric symptoms such as paranoia, anxiety, and psychosis. Studies have found, however, that CBD may help mitigate these effects.
Because the laws regarding the use of cannabis and cannabis products are rapidly changing, you should always check your state's laws before using products containing CBD or THC.
Typically sourced from hemp.
Both THC and CBD are stored in body fat, which means that both can potentially be detected on drug tests for some time after you have stopped using them.
While THC and CBD share similarities, there are some key differences between the two compounds.
Steven Gans, MD is board-certified in psychiatry and is an active supervisor, teacher, and mentor at Massachusetts General Hospital.
CBD can also be taken orally as a tincture, oil, capsule, or spray. Edible CBD products are also popular and include gummies, candies, and beverages.
THC and CBD have an effect on the endocannabinoid system, a system that plays an important role in maintaining homeostasis. Researchers are still working to understand the ins and outs of this complex system, but they do know that it is associated with processes including memory, appetite, sleep, mood, and fertility.
How to Take THC and CBD.
While CBD can come from either hemp or marijuana, it is often derived from hemp in order to avoid the addition of larger amounts of THC. THC, on the other hand, is derived from marijuana.
Cannabis contains over 113 different chemical compounds known as cannabinoids. Cannabidiol (CBD) and delta-9-tetrahydrocannabinol (THC) are two types of chemical compounds derived from cannabis. In recent years, interest has grown in the potential health effects and benefits of cannabis. Much of this interest has centered on these two cannabinoids.
Before choosing a THC or CBD product, it is important to check your state laws to ensure that these products are legal where you live. Federal law mandates that hemp-derived CBD products should contain less than 0.3% THC, but even those trace amounts are still illegal in some states.
THC, on the other hand, does have psychoactive effects. It is the compound that produces the high that people associate with marijuana.
Non-psychoactive (does not produce a high)
It can also be added to lotions and salves to apply to skin. It is important to note that the effects of these topical products will be localized since they are not being ingested.