cbd thc chartDecember 15, 2021
2:1, 4:1, 5:1 – A balanced product that can provide optimized levels of both CBD and THC for medicinal use, based on the fact that higher doses of CBD are often needed for relief. Can be intoxicating.
1:1 – Equal amounts of THC and CBD. A good option to try for all kinds of pain, including neuropathic pain. Products with a 1:1 ratio can be uplifting but this ratio will most likely cause impairment if using the suggested serving size. Always start low, go slow, to avoid intoxicating effects.
While everyone is different, the following guidelines work for most people:
Understanding CBD:THC Ratios.
We realize that it can feel overwhelming when researching cannabis for pain. There are so many options—different types of products and different ratios.
For example, you might use a shorter-acting sublingual pill or vape to bring instant relief, together with an edible or transdermal patch to get you through the night.
We recommend consulting with a clinician before combining cannabis (which includes CBD hemp products!) with pharmaceuticals or over-the-counter pain medications.
If you’re using products containing THC (the cannabinoid that can be intoxicating and make you feel “high”), you’ll want to be careful with your dosing to make sure you don’t get end up with too much THC. The best approach is to start low and slow.
THC: The cannabinoid responsible for the “high,” if used in large enough amounts. Cannabis products containing over 0.3% THC remain illegal at the federal level and can only be legally purchased in states that have legalized recreational or medical marijuana.
Have you ever woken up in the middle of the night when your pain medication wore off, and suffered as you re-dosed and waited for the medicine to kick in? Fortunately, with CBD and THC products, you can layer different product types to reduce the changes of this happening.
The ratio indicates the amount of CBD compared to the amount of THC.
What’s the Best CBD:THC Ratio For Your Pain?
Leaf411’s supporting members offer many different CBD:THC ratios to meet different needs.
Once you start looking at other cannabis products, including vapes, you’ll notice ratios on many—but not all—product labels. Common ratios include 1:1, 5:1, 10:1, and even 20:1. What do these numbers mean? And how do they help with your pain?
20:1 – High CBD levels along with very low THC levels provide a good option for managing inflammation pain. Very rarely intoxicating.
What if a product doesn’t list a ratio? In that case, look closely at the product label. The chances are good that the product either contains all CBD, with little or no THC (legal CBD hemp products fall in this category), or the product contains all THC.
While you cannot overdose on THC, the feeling of being “too high” can be uncomfortable. Our website provides tips for what to do if you feel too high.
Timing Your Dose: How Different Cannabis Products Reduce Pain.
Our Leaf411 hotline nurses have both specialized training and experience helping people to find the best option for their particular situation. We’d love to share our expertise with you as well! Reach out to us on our free, anonymous hotline at at 844-LEAF411 (844-532-3411).
Depending on how you use cannabis and other medications, there can be possible medication interactions. Our Leaf411 library offers guidance on specific medication interactions here.
Understanding the roles that both CBD and THC play in managing pain can help you find the best product for your needs. If you need a quick refresher on the types of pain that CBD and THC work best on, check out our previous post here.
Research on cannabis as a safe alternative for treating pain continues to grow. As nurses, we’ve heard and seen firsthand the power of this plant-based medicine, and we stay up-to-date on the latest findings and clinical guidelines for using cannabis for pain.
Whether you’re looking at CBD hemp or cannabis containing higher levels of THC (sold legally in dispensaries), you have several different routes of administration to choose between :
Be sure to closely look at the product label to make sure you understand the ratio! While it’s not as common, some manufacturers state the ratio reflecting the THC first and the CBD content second, like our member incredibles 10:1 THC:CBD tincture.
Popular ways to take CBD include:
$55 per container.
Some CBD products do some of this math for you and illustrate how many milligrams are in a milliliter, some even marking these points on the dropper so you know exactly what you’re taking.
Expressed in milligrams (mg), CBD dosage largely depends on the conditions and symptoms you’re trying to treat and your unique endocannabinoid system, which is associated with motor control, behavior, emotions, the nervous system and homeostasis. CBD dosage remains an area of active research—more large, high-quality studies are needed in different populations to determine appropriate dosing, efficacy and safety guidelines.
Like with any substance, you can take more CBD than your body can handle. Studies show doses up to 1,500 milligrams a day have been well-tolerated, but every person is different  Bergamaschi MM, Costa Queiroz RH, Zuardi AW, Crippa JAS. Safety and side effects of cannabidiol, a Cannabis sativa constituent. Current Drug Safety. 2011;6(4):237-49. . Ingesting too much CBD can cause unpleasant side effects, such as dry mouth, nausea, diarrhea, upset stomach, drowsiness, lightheadedness and general disorientation. While rare, liver damage can also occur.
How to Take CBD.
The medical and research community still has a long way to go before figuring out what dose works best for each condition. At an individual level, consumers can experiment with caution until they find what works best for them.
With that said, ingesting CBD via gummies or other edibles may take longer to take effect since the CBD has to travel to your digestive system to be broken down and absorbed.
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Without FDA approval, there is little guidance in the U.S. on how much CBD a person should consume for various conditions.
(Note: All prices are accurate as of publication and are subject to change.)
CBD oil, on the other hand, makes it easier, to begin with a small dose. But calculating CBD oil dosage can be less straightforward. Oils and tinctures tend to come in a dropper bottle and, typically, only the total liquid volume and CBD contents are listed on the label. For example, the label might simply state there’s 1,500 milligrams of CBD in the 30-milliliter bottle.
Several countries, including Canada and those in the U.K., have approved the use of Sativex, an oral spray with equal amounts of CBD and THC, to treat pain stemming from multiple sclerosis. Canada has also approved it for treatment of cancer pain.
Each drop contains 2.5 milligrams of CBD.
*Dosages are based solely on small, short-term clinical study results where CBD proved significantly successful over placebo. Much larger studies are needed to further strengthen the evidence.
Cannabinoids generally have a low bioavailability compared to other substances, according to Jordan Tishler, M.D., a physician specializing in cannabis treatment in Massachusetts. However, “products that contain emulsifiers like egg yolk (brownies) or lecithin (some gummies) do better,” he says.
Penguin CBD Oil.
At the end of the day, not all supplements are created equal, which is why it’s important to work alongside a healthcare provider when adding CBD to your wellness regimen and research reliable brands. And while emerging research and anecdotal evidence is promising, more large, randomized-controlled trials are needed to further understand the benefits of CBD and its dosing.
But what does 1 milliliter look like? Due to the current lack of regulation of CBD, this calculation can be tricky. Start by figuring out the volume of a single drop in your dropper, which is usually 0.05 milliliters, according to Dr. Bugailiskis. If you’re unsure, ask the company.
$45 per container.
If you’re still not sure where to start, mydosage.com offers a questionnaire and CBD calculator to help you based on your specific symptoms and usage goals.
This bottle contains 50 milligrams of CBD per milliliter. Let’s see how many milligrams are in a drop:
Your CBD product of choice will largely depend on your personal preferences, as well as your budget since prices vary depending on the potency of ingredients and manufacturing processes. Different mediums also offer varying levels of bioavailability—or how much of what you take is actually absorbed into your bloodstream to have an effect. For example, if you ingest 10 milligrams of CBD via 1 milliliter of liquid, your body might absorb about 60% of it, or about 6 milligrams.
Cannabidiol (CBD) is growing increasingly popular, thanks to its many purported health benefits and non-psychoactive properties (most CBD products contain less than 0.3% tetrahydrocannabinol, or THC). As research evolves and sheds light on CBD’s efficacy, especially for pain relief, more and more people are adding it to their daily wellness regimens.
How to Calculate CBD Dosage.
$45 per container.
25mg÷2.5mg/drop = 10 drops 10 drops ×2.5mg = 0.5mL.
Here’s where math comes in. Let’s continue with the 30-milliliter bottle with 1,500 milligrams of CBD and 0.05 milliliters in a single drop as our example.
With the exception of one CBD product, a prescription drug used to treat seizures associated with particular syndromes, the Food and Drug Administration (FDA) doesn’t regulate the use of CBD. (In fact, it’s illegal to market CBD as a supplement or add it to food.) Therefore, it’s best to consult a doctor with experience in CBD administration to determine your ideal dosage.
$45 per container.
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1500mg÷30mL = 50 mg/mL.
Next, you can calculate how many drops you need to reach your goal dosage. Let’s say you want to consume 25 milligrams each day.