entourage cbd

December 15, 2021 By admin Off

CBG is the final form of CBGA, which is sometimes called the “stem cell” cannabinoid. Scientists have researched the potential antimicrobial and digestive benefits of CBG .

The Entourage Effect is the term used to describe the enhanced effects of cannabinoids, such as CBD, when multiple compounds synergistically work together rather than alone. That synergistic effect is known as the Entourage Effect.

Although found in minor amounts, they still play a crucial role in the synergistic effects of CBD products. You would be surprised at how they always make a difference even at those minor amounts.

Cannabichromene (CBC)

Don’t forget the analogy of the two basketball teams. Which team do you think would win? The team with five players working together to shoot, pass, defend, rebound, or the team with just one player doing everything?

Scientists have identified thousands of them throughout nature, and some are known to be only found in cannabis and hemp. The flavonoids found in hemp and marijuana are called cannaflavins .

Guaiol has a piney flavor and aroma, and this terpene may offer antiparasitic benefits . Like many other terpenes, guaiol also appears to have antioxidant effects.

CBN can be produced by aging THC or converting CBD. Many people who use CBN believe that this cannabinoid has sleep-promoting properties , and CBN has been investigated for its potential neuroprotective benefits .

The hemp plants’ genetics, the extraction method, and the parameters used, and the purification process are three of the several crucial parts of the manufacturing process.

In a study conducted in 2011 , they found flavonoids to posses the following properties:

Imagine two basketball teams playing against each other. Team red has only one player doing all the shooting, stealing, defending, and rebounding, while team blue has all five players working together doing different things. Which team would win? Obviously team blue will win.

Not All Hemp Extracts Are Equal.

It started In 1998 when Professors Raphael Mechoulam and Shimon Ben-Shabat found the Endocannabinoid System demonstrated an “entourage effect” when they noticed the plant compounds significantly increased the activity of our receptors.

Found in lavender as well as hemp, linalool appears to have impressive antimicrobial benefits . This terpene also interacts with your nervous system, and it might help with depression and anxiety .

CBC is a little-known cannabinoid that has been investigated for its potential analgesic benefits . Scientists have researched the activity of CBC at the nervous system’s TRPV1 receptors, which regulate inflammation and pain .

Since it interacts with your brain’s CB2 receptors, beta-caryophyllene works like a cannabinoid. It doesn’t get you high, however, and this terpene is believed to have potent anti-inflammatory benefits .

Flavonoids make the yellow of sunflower pop out against a sunny blue sky and give blueberries their name. However, studies have shown these compounds possess many health benefits.

What is Cannabinol (CBN)

Other notable cannabinoids are Cannabidiolic Acid (CBDa), Cannabidivarin (CBDV), Cannabicitran (CBT), or Tetrahydrocannabivarin (THCV).

Our team at Colorado Botanicals holds decades of experience in each part of the hemp manufacturing process. From the farms to growing hemp organically, the post-process of farming in drying the plants to the crucial extraction and purification process to retain as many cannabinoids, terpenes, flavonoids, and other important plant oils as possible.

If you’re looking for a product that maximizes the full potential of the Entourage Effect, visit our wide variety of products such as our CBD oils , CBD gummies , CBD creams , CBD softgels , or our CBD face mask.

Just because two companies manufacture CBD oil does not mean the quality is close in terms of effectiveness and safety.

The first two parts mentioned can be exceptional. Still, if the purification process cannot retain the essential cannabinoids and lighter compounds such as terpenes and flavonoids, it doesn’t make much of a difference.

Cannabinoids work better with a combination of cannabinoids, terpenes, and flavonoids versus a CBD product with fewer compounds or, even worse, just pure CBD.

Compounds most supportive of human health and wellness come from the trichomes, seeds, and tissues found in the hemp flower, as shown in the adjacent diagram.

WholeFlower tinctures are designed for customers dealing with the most stubborn chronic and acute conditions. Because the oil is administered sublingually, it does tend to act faster, making it perfect for immediate impact and rescue.

In the tradition of directed innovation, Entourage Hemp ™ presents 50mg WholeFlower Microcaps : highly-potent, but impossibly small CBD softgels. At just 0.25ml, the microcaps are the size of a pea but deliver a whopping 50+mg of full-spectrum CBD each. Like our leading WholeFlower tinctures, microcaps contain a balanced blend of cannabinoids, terpenoids and flavonoids, all delivered on the finest organic hemp seed oil. Perfect for customers that need a bit more CBD potency in their daily regimen.

Surging demand for better sleep has given rise to our latest product: Entourage Hemp ™ D eep Sleep Microcaps. This proprietary formula features 20mg of cannabinol (CBN – the sleep cannabinoid) buffered with 20mg of CBD and 4mg of CBDV. Th ese are the strongest CBN softgels available in the market and to make things easy, we put them in our small 0.25ml microcap format.

At Entourage Hemp ™ we've focused on perfecting the delivery systems that people like the most and work the best. We've directed our energy to broadening our understanding of the plant, and we've doubled-down on quality, potency, and transparency. It all started with a simple plan back in 2013: make clean and potent CBD products and sell them at a good price. That same philosophy still drives what we do today.


Available in a 4.16ml dropper vial or 10ml dropper bottle.

Entourage Hemp ™ WholeFlower CBD tinctures are without exception the highest potency tinctures available in the market. Whereas most sublingual tinctures top out at just 3.33% (1,000mg in 30ml bottle) our WholeFlower tinctures go to 25% potency. That means that a full 25% of the volume of the bottle is comprised of active phytocannabinoids like CBD, CBDA, CBG, CBN, CBC, and others.

Deep Sleep Microcaps contain no THC and are av ailable in 10-ct pharmaceutical blister packs: 10, 30 and 60 to a box.

The WholeFlower Principle at Entourage Hemp ™ is a guiding philosophy for all of our product development, whereby we endeavor to maximize the use of these compounds in our products. Stated simply, we use the WHOLE FLOWER in our products rather than isolated or synthesized individual components. This results in better product performance and cleaner, more natural effects.

Entourage Hemp™ Soothing Salve and Healing Balm are the newest additions in the product lineup. Made from natural and organic base ingredients combined with our proprietary blend of essential oils, hemp seed oil, hemp extracts, and hemp distillates. Perfect for immediate relief on the go.

Available in convenient pharmaceutical blister packs. 30 and 60-ct boxes.

Entourage Hemp ™ : Indulgence for the Senses and Contentment for the Soul.

Entourage softgels deliver a measured, unit dose of CBD and other phytocannabinoids in a convenient, clean format. They are perfect for daily use, and a fixture in any health and wellness regimen. Each Entourage Hemp™ full-spectrum softgel contains 15mg of total cannabinoids and dozens of other naturally-occurring, vital compounds from the plant. A perfect blend of CBD and minor cannabinoids make up each softgel, carried in beautiful, cold-pressed, organic hemp seed oil.

Available in a 60-ct bottle.

At Entourage Hemp™ our products that are rigorously tested, precisely manufactured, convenient to use, and fairly priced. We work with academic research hospitals, board-certified physicians, and caregivers to optimize product design and delivery. As pioneers in 50-state legal cannabinoid products we set an early standard for many of the industry practices that are now expected: ISO-based manufacturing controls and quality systems; 3rd-party analytical testing; post-market surveillance and product traceability; reliable delivery systems, unit-dosing and compliant packaging. We have active research and development platforms in cannabis therapeutics, food, fiber, and materials science through our holding company, Cannoid, LLC. We also do custom formulation and product development for leading manufacturers and researchers.



Stress is everywhere and can be found in everything around us. All around the world, people face different kinds of stressors and feel stress in different forms – a headache, body ache, or any other manifestations. Different people handle stress in a myriad of ways and some can face stress more easily than others. CBD oil is one way to help cope with stress and help the body restore itself; because of the relaxing properties of CBD oil, this helps the body calm down in stressful situations much like during an anxiety attack, or to help a person wind down after a hard day’s work. Insomnia is one effect of stress and CBD oil has been found to work effectively in combating insomnia; as it induces a full relaxation on the body, giving the person a restful sleep, waking up energized in the morning and feeling fully refreshed.

The best CBD products for those that experience severe pain or chronic pain, aside from the creams and lotions, can also be tinctures. By taking the tincture sublingually, you allow the CBD to quickly enter the bloodstream. Once inside it will find its way to the affected areas. CBD is a fat soluble molecule and needs to build up your fat cells in order to be readily available when it is needed most. CBD works by stopping the breakdown of anandamide which helps the body relieve pain and by regulating the production of the inflammatory molecule cytokines which can lead to reduced inflammation and pain. The tinctures also work great for relieving headaches, nausea, or even the discomforts of chemotherapy treatment.

When it comes to pain relief, CBD oil is also said to be beneficial. When the brain releases a pain signal; the endocannabinoids get into action, locating the area and then relieving the pain. However, for severe or chronic pain, the body may not produce enough endocannabinoids to fully restore the balance and here is where CBD oil comes into play; boosting the body’s processes and helping to relieve the pain. In ancient China, leaves of the Cannabis Sativa plant are made into poultices and applied to body parts that are inflamed or in pain.

To date, further research and studies are still needed and debates are still ongoing, but advocates of CBD oil are promoting its use for anxiety, pain, stress, inflammation, and cramps. How exactly does CBD oil work? Derived from Cannabis Sativa, the extract is a mixture of organic hemp oil accompanied by oils such as coconut oil and can be either an isolate or full-spectrum. The cannabinoids in the oil interact with the body’s natural endocannabinoid system – an important neurochemical system for establishing and maintaining human health. It plays a huge part in maintaining the body’s homeostasis, or ‘natural balance’ and the hormones and receptors that are found in the entire body help maintain and regulate various functions- some of which include sensory perception (responsible for pain), immunity, mood, nerves, and sleep. Every time one of these body functions are not in sync or not at their best, the endocannabinoids work to put them back in their normal state.

Entourage CBD works hard to ensure that high-quality hemp plants are grown for their CBD products and that the extraction processes meet standards of excellence so that customers are purchasing only the best CBD oil. Entourage CBD believes in the “entourage effect” of CBD – the therapeutic effect of over 100 cannabinoids present in the hemp plant interacting with each other – the terpenes, and the flavonoids, thus providing the best effects for the CBD oil. Entourage CBD continues to commit to further research and development of CBD products so that more knowledge can be shared with customers on the benefits and effects of CBD oil to the human body and how it should be part of the all-natural, high-quality holistic approach to health and wellness.

CBD For Stress.

CBD oil interacts with the body’s endocannabinoid system to ensure that the body reaches homeostasis. Compared to sleeping pills, CBD oil does not induce drug dependency and since it is almost THC free, it does not interfere with the mind’s normal functions. Further research is needed, but for some people, they find that CBD oil is helpful to their mental health and functions. Some students find themselves able to study better and retain more of what they learn with the help of CBD oil. Others report that CBD oil has helped provide mental clarity when dealing with stressful decisions, thus enabling them to go for better choices. The best CBD products for stress can be tinctures and any form that it comes in.

Modern science has turned this same application into a handier form that is also easier to apply – via pain creams and lotions or rubs. The CBD oil is infused with other organic ingredients such as organic coconut, vitamin E, jojoba seed, avocado, sunflower, and neem oils as well as aloe and rosemary extracts. Wher most CBD creams have a difficult time penetrating the skin, our unique formulation includes DMSO (dimethyl sulfoxide) which opens up the pores and helps the CBD penetrate the skin more quickly. This combination is an effective product for applying directly to inflamed and painful areas such as joints, muscles, head, back, legs, arms, and most places on the body. While more studies are needed to confirm this; CBD is found to have properties that reduce inflammation and swelling, therefore providing much-needed relief for minor injuries or those with chronic pain. Of course, CBD oil is a healthier alternative to most common pain relievers because it is all-natural and will not leave lasting damage on the liver when taken for long periods. CBD pain creams are also seen as a better alternative to over-the-counter rubs and creams which may contain chemicals that can irritate the skin.

Cannabidiol oil, more commonly known as CBD oil, has seen a rapid rise in popularity in a very short amount of time. CBD was first discovered in 1940 by Roger Adams of Harvard University. One of the early studies on cannabinoid compounds conducted in 1946 by Dr. Walter S. Loewe showed that while THC was intoxicating to animals, CBD was not. In the 1960’s tests were done on primates and CBD oil for therapeutic use was launched by British pharmacologists. In 1980, Dr. Raphael Mechoulam; (often thought to be the discoverer of CBD), tried to test whether CBD oil can be helpful in epilepsy treatment.

Due to the anti-inflammatory properties found in CBD, advocates believe that this is helpful in the overall immune system of a person. As most of the autoimmune diseases are caused by inflammation, CBD can very well possibly be able to combat these inflammations in the brain. Research is still insufficient, however, but more and more people are pushing for the study of the anti-inflammatory properties of CBD and how it can be a huge factor in strengthening the body’s immune system. Since it already works with the body’s endocannabinoid system in restoring homeostasis in the human body, reducing inflammation is quite possibly one of its benefits. CBD tinctures are the best form to take for maximum support for the immune system.

Advocates have recommended the use of CBD oil for anxiety relief, mainly because it is all-natural and organic. Also, CBD oil has very little side effects compared to prescription pharmacological medications; which may induce side effects such as tremors, nausea, or drug dependence. There is also a danger in overdosing on the usual prescription medication which can result in liver damage or interference in the general mental health of a person. With CBD oil, there is no danger of overdosing. Largely due to its form, CBD oil is found to work quickly in providing anxiety relief especially if applied sublingually. This is good news for the ones who struggle with anxiety attacks and would prefer a method that is inconspicuous and unobtrusive but provides immediate relief. The best CBD products to use for anxiety would be tinctures or vapes. Gummy candies can also be an inconspicuous form to use but they may take longer than tinctures to take effect.

However, there are times when the body’s endocannabinoid system needs a little more of a push, and this is where CBD oil can come in handy, helping the body regulate itself and nurse itself back to a better state. Keeping in mind the very low levels of tetrahydrocannabinol (THC) at just 0.3%, there is no psychoactive component; therefore CBD oil does not have the ‘high’ or ‘euphoria’ commonly associated with marijuana, and this means a person can keep using CBD oil for as long as it is deemed necessary.

Muscular cramping is common to athletes, but can also be felt by other non-athletes and most can agree; it is not a pleasant feeling. Most menstruating females experience cramps almost every month, and while it is not a problem for some, others get very painful ones that interfere with their normal lives. CBD oil can be a helpful treatment for cramps and the discomforts that come with it as it relaxes muscular tension. Much like the way it works for pain relief, CBD interacts with the endocannabinoids to provide the needed balance for the body. Topical applications, like pain creams and lotions, are best for targeting the body cramps and providing quick relief because they are applied directly to the area.

CBD For Pain.

CBD For Anxiety.