high cbd oil effectsDecember 15, 2021
Like THC, CBD can also be consumed in a number of different forms. CBD oils can be formulated for vaping, although there have been recent concerns about the health dangers posed by vaping.
This interest is likely to continue to grow as cannabis and marijuana products become legal in more states. A number of different products have emerged that contain CBD, THC, or both that are designed to alleviate ailments such as stress, anxiety, and insomnia. In order to understand the side effects and potential benefits of these products, it is important to first understand the differences between CBD and THC.
Before choosing a THC or CBD product, it is important to check your state laws to ensure that these products are legal where you live. Federal law mandates that hemp-derived CBD products should contain less than 0.3% THC, but even those trace amounts are still illegal in some states.
Cannabidiol, usually referred to as CBD, is the second most prevalent chemical compound found in cannabis. First discovered during the 1940s, CBD has recently become more popular as a natural treatment for a range of conditions. It can be derived from hemp or from marijuana. Hemp-derived CBD still contains trace amounts of THC, while marijuana-derived CBD may contain more.
However, while these substances appear safe, that does not necessarily mean that you won't experience some unwanted effects. Some adverse effects that have been reported include:
NIDA also notes that THC alters how the hippocampus and orbitofrontal cortex function. These areas of the brain are important in the formation of new memories and the ability to shift attention from one thing to the next. This not only affects a person’s ability to learn and form new memories, but it also makes it difficult for people to perform difficult tasks.
Some research suggests that CBD and THC are generally safe and result in few side effects.
Some evidence suggests that the combined effects of CBD and THC may be dependent on dose. A 2019 study, for example, found that low doses of CBD actually played a role in amplifying the psychoactive effects of THC, while high doses of CBD reduced THC’s effects.
Cannabis contains over 113 different chemical compounds known as cannabinoids. Cannabidiol (CBD) and delta-9-tetrahydrocannabinol (THC) are two types of chemical compounds derived from cannabis. In recent years, interest has grown in the potential health effects and benefits of cannabis. Much of this interest has centered on these two cannabinoids.
Psychoactive (produces a high)
CBD and THC have the same molecular structure, but there are differences in how these molecules are arranged that are responsible for the differing effects they have. By mimicking endocannabinoids, they bind with receptors and cause different effects in the body.
Typically sourced from hemp.
Kendra Cherry, MS, is an author and educational consultant focused on helping students learn about psychology.
Although CBD in certain forms is legal in most states, the specifics of the legality of any THC or CBD product can vary from one state to the next. Several states have also approved the use of marijuana and THC for recreational purposes.
While research on the potential health benefits of THC, CBD, and other cannabinoids is still in the early stages, there is evidence that these substances may be helpful for conditions including:
What Is CBD?
Marijuana itself can have a number of short-term and long-term adverse effects, including impaired short-term memory, altered judgment, and impaired coordination. Research also suggests that marijuana can alter brain development and may lead to cognitive impairment.
Some research suggests that the potential therapeutic effects of THC and CBD tend to be greater when the two cannabinoids are taken together at the same time. This phenomenon is known as the entourage effect.
CBD that comes from marijuana may contain more THC, which may not be ideal for people who are trying to avoid THC. Some CBD products that are produced from cannabis, for example, may contain more THC than the label suggests.
CBD can also be taken orally as a tincture, oil, capsule, or spray. Edible CBD products are also popular and include gummies, candies, and beverages.
THC, which may be administered as medical marijuana, may be used to alleviate symptoms of a number of conditions. It may be helpful for conditions such as:
It is also important to remember that CBD and THC work in a number of different areas of the brain and researchers do not yet fully understand the effects that these cannabinoids have, either alone or in conjunction with one another.
CBD is often used to alleviate symptoms associated with:
Before You Take THC or CBD.
Neurotransmitters are chemical messengers that relay signals between nerve cells in the body. They play an important role in a wide range of functions including sleep, pain, appetite, mood, and the immune system.
When choosing products containing CBD or THC, it is also important to consider their legality. Both marijuana and THC are included in the U.S. Controlled Substances Act, which means that they are not legal under federal law. As of July 2020, 33 states and Washington, D.C. have enacted policies allowing medical marijuana and products containing THC to be prescribed by a doctor. Some states also allow recreational use of marijuana and THC-containing products.
The product you choose may depend on the effects you are trying to achieve. If you are trying to reduce stress or sleep better, for example, CBD may provide benefits without the negative side effects associated with THC. THC might be a better choice for symptoms or conditions for which the substance has demonstrated benefits, such as tremors or poor appetite.
Steven Gans, MD is board-certified in psychiatry and is an active supervisor, teacher, and mentor at Massachusetts General Hospital.
Because THC is the main psychoactive substance in marijuana, it can be detected on most standard drug tests. CBD may be detectable as well, but many drug tests are not designed to look for cannabidiol.
While CBD and THC often have similar effects and are often used to treat many of the same ailments, there are some differences.
Delta-9-tetrahydrocannabinol, or THC, is the main psychoactive ingredient in cannabis. According to the National Institute on Drug Abuse (NIDA), THC activates the brain's reward system by signaling the release of the brain chemical dopamine. Dopamine is a neurotransmitter that plays an important role in mood and pleasure. By triggering a higher-than-normal release of dopamine, THC causes people to experience feelings of euphoria. THC is often administered by smoking marijuana, but it can also be found as an ingredient in capsules, edibles, and oils.
However, many CBD products do contain trace amounts of THC. While these amounts are small, they may still be detectable if you are consuming large quantities of CBD or if the products you are using contain more THC than the packaging label claims.
Alternative medicine practitioners believe these compounds provide more important health benefits, but there's no clear evidence to support this.
People that support the use of CBD claim that CBD oil can treat a variety of health problems, including:
CBD oil may also increase liver enzymes (a marker of liver inflammation). People with liver disease should consult their healthcare provider before taking CBD oil and use it with caution. Regular blood liver enzyme level checks are recommended.
Don't drive or use heavy machinery when taking CBD oil since some of them contain THC. This is especially important when you first start treatment or use a new brand.
For the study, nine healthy men took either 600 mg of CBD or the same dose of a placebo. The men who took CBD had lower blood pressure before and after stressful things, like exercise or extreme cold.
Are CBD Oil and Hemp Oil the Same?
Don’t take CBD oil if you’re pregnant or breastfeeding. The American Academy of Pediatrics advises pregnant women to avoid marijuana because of the potential risks to a baby’s development. Although the effects of CBD itself are unclear, CBD does pass through the placenta.
However, CBD affected each type of addiction very differently.
Some experts suggest CBD may help treat cannabis and nicotine dependence, but more research is needed.
A 2017 study reported that only 31% of CBD products sold online were correctly labeled. Most contained less CBD than advertised, while 21% had significant amounts of THC.
In June 2018, the U.S. Food and Drug Administration (FDA) approved Epidiolex, a CBD oral solution.
CBD's exact mechanism of action is unclear.
The researchers reported that CBD showed promise in treating people with opioid, cocaine, or psychostimulant addiction.
There aren't many study trials that look at CBD's anxiety-relieving effects in humans. One of the few is a 2019 study published in the Brazilian Journal of Psychiatry .
Drugs that could potentially interact with CBD include:
CBD oil may treat pain, lower anxiety, and stimulate appetite the same way that marijuana does, but without affecting your mental state. CBD might also help treat some types of seizures.
Remember that CBD oils are mostly unregulated, so there's no guarantee that a product is safe, effective, or what it claims to be on its packaging.
There are no guidelines for the proper use of CBD oil. CBD oil is usually taken by placing one or more drops under the tongue and holding it there for 30 to 60 seconds without swallowing.
However, there’s no evidence CBD oil can treat high blood pressure on its own or prevent it in people at risk. While stress can complicate high blood pressure, it can’t cause it.
However, there aren't many studies that examine the use of CBD in treating chronic pain in people. The studies that do exist almost always include THC. This makes it hard to isolate CBD's unique effects.
One interesting piece of research is a 2012 study published in the Journal of Experimental Medicine . Researchers injected rats with chemicals that prompt inflammation. Then they gave the rats CBD.
CBD oil is made from the leaves, stems, buds, and flowers of the Cannabis indica or Cannabis sativa plant and should contain less than 0.3% THC. Hemp oil is made from the seeds of Cannabis sativa and contains no TCH.
CBD oil is an extract of Cannabis indica and Cannabis sativa , the same plants used to make marijuana.
There’s some evidence CBD interacts with seizure medicines like Onfi (clobazam) and boosts their concentration in the blood. More research is needed, though.
However, at higher doses, too much activity at the receptor site can lead to the opposite effect. This would take away the helpful effects of CBD.
Of course, never make changes to your medication regimen without your doctor's OK.
However, CBD oil might change the way your body breaks down certain medications. This could make the drugs have a stronger or weaker effect, which can be dangerous. Talk to your doctor before you use CBD oil, especially if you take any medicine or have liver disease.
Doctors may prescribe medical marijuana to people with pain that’s resistant to treatment, like those with terminal cancer. There’s some evidence that CBD plays a role in this benefit.
CBD oil might help relieve stress, anxiety, seizures, drug withdrawal, and nerve pain. But taking higher doses doesn't always mean they'll have a stronger impact. Also, many studies on CBD have been done on animals, so it's hard to tell if these same effects will apply to people.
The study suggests CBD oil may be a good complementary therapy for people whose high blood pressure is affected by stress and anxiety.
You might experience nausea, diarrhea, or dizziness when you take CBD oil. Don't take CBD oil if you're pregnant or breastfeeding. Also, CBD oil affects the way your body breaks down certain drugs, so talk to your healthcare provider if you're on any medications.
CBD is an herbal remedy –a treatment that comes from a plant — in this case it is the cannabis sativa plant. Cannabis sativa has been used for thousands of years for its healing and for mind-altering effects.
By acting on the ECS, CBD may have many different effects on the body. Examples include: balancing the body’s overall physical functions (homeostasis), reducing pain sensation, and lessening the body’s reaction to injury or infection (inflammation).
Already tried CBD? There are many other ways to reduce back pain or insomnia that do not involve taking it. Learn about some other methods that Goodpath's integrative medicine approach uses to reduce your symptoms here:
What Is CBD?
There are also studies of oral, topical, and inhaled CBD for use in many other conditions including: dystonia (movement disorder), Fragile X syndrome (rare genetic disorder), graft-versus-host disease (bone marrow transplant rejection), multiple sclerosis (MS), opioid withdrawal, schizophrenia, and smoking cessation. CBD is also used to alleviate Parkinson’s symptoms, but there are some studies that advise against it.
CAUTION : CBD should not be used with medicines that are prescribed to control seizures.
Applications of transdermal cannabidiol were studied in people with temporomandibular (joint of the jaw) disorders (TMD) that caused myofascial (coverings of muscle) pain. Those studied had less muscle activity and pain after applying the topical CBD for 2 weeks .
Studies are ongoing, but there is evidence that CBD may be effective in reducing anxiety, chronic (long-term) pain like back pain , and insomnia or trouble sleeping .
The takeaway about CBD is that the initial research is promising but there is still much to learn. It may help with some conditions like long-term pain and sleep.
An animal study found transdermal CBD lessened the pain and inflammation of arthritis .
What Are the Medical Uses of CBD?
CBD, or cannabidiol , is recommended for everything from anxiety to indigestion. And, people are also using it for a wide variety of reasons.
Because it is so widely available and recommended for so many problems, it must be used carefully and purchased from reliable sources.
CAUTION : Fatty foods may increase how CBD is absorbed by the body.
The National Academies of Sciences (NAS) found significant evidence that cannabis was an effective treatment for long-term (chronic) pain. However, much of the research was done outside of the U.S. And the forms of cannabis studied in the U.S. were not the same as those commonly used .
Early research on CBD for the treatment of insomnia suggests that it may be effective. Additional studies are needed .
Observational studies and randomized controlled trials (RCTs) of the effectiveness of cannabinoids in chronic noncancer pain found a 30% reduction in pain in 1 out of 3 of those using cannabinoids. This was considered significant .
As stated above, CBD is in a class of chemicals called cannabinoids . Because it comes from a plant, it is called a phytocannabinoid .
Early research suggests that 160 mg of cannabidiol before bed significantly improves sleep duration compared to a placebo in patients with insomnia. Smaller doses did not have this effect. Also, patients did not feel drowsy the next morning morning .
Topical cannabidiol oil was studied in 29 people with lower limb peripheral neuropathy. After using the oil for 4 weeks, the people had less intense and sharp pain and fewer other uncomfortable sensations .