how long before cbd oil takes effectDecember 15, 2021
One of the biggies: How long does it take for CBD oil to work? Because who hasn’t been in the situation where it seems like one person takes CBD and turns into a zen mother earth goddess right away, while you’re sitting over here waiting for something (anything!) to happen to take your morning anxiety away. (What’s that saying? A watched mug of CBD coffee never kicks in?)
“Every day consistency is key,” he adds. “Rome wasn’t built in a day.” He encourages people to think of CBD as a dietary supplement and notes that it can take up to four to six weeks to “fully realize the benefits of CBD,” especially if you’re taking it to alleviate anxiety, pain, or for stress relief. “We are all unique in our needs and bodily systems. Some people experience rapid and very noticeable benefits while others notice benefits over time and daily use, which is common for many dietary supplements,” Stanley says.
Turns out, CBD isn’t one-size-fits-all. Various factors—such as the amount you take, the form you take it in, and where you got your CBD from—can all impact how long it takes to work, says Brooke Alpert, RD, the founder of Daily Habit, a line of CBD powder.
Charlotte’s Web co-founder Jesse Stanley adds that CBD products often come in different strengths and thus the amount of CBD that works for your bestie may not work for you. “You might need to try a few strengths until you find what works for you,” he says. (Good to know!)
It’s worth noting that the research on taking CBD sublingually (science-speak for under your tongue) is mixed: As Well + Good has previously reported, many studies on the subject have included both CBD and THC, so it’s hard to generalize the findings to products that are just CBD-based. However, chemist Jesse Kater previously told tell Well+Good that “most of the literature supports the notion that CBD has better bioavailability when consumed sublingually versus orally.” That supports anecdotal evidence that CBD starts working almost immediately when taken under the tongue. Alpert agrees to an extent, saying that it can take anywhere from 10 minutes to an hour to kick in when taken sublingually.
The reality: Trial and error is the name of the game when it comes to finding the correct amount CBD that will actually work for you. With a little research, you’ll hopefully find the right amount for you that gives you the results you’re aiming for.
The most important factor, Alpert says, is quality. There is so much variance among CBD products, and that can also impact how long it takes before you start feeling any effects. “This is where people are getting frustrated with CBD, because they’re like, ‘Well, I got a CBD gummy from my local bodega and I didn’t feel anything,’” Alpert says. Some things Alpert and Stanley say you should consider when shopping for any CBD product:
For example, if you’re putting your CBD product in a coffee that has almond milk or sugar or anything else that might need to be digested, your CBD will kick in more slowly than it would if you put a few drops directly under your tongue. “I look at it the same way I talk to people about their sugar consumption,” Alpert explains. “If you have juice or put a little bit on your tongue, it’s going to be an immediate reaction versus when it’s in fruit where you have fiber, which slows down absorption.” (Generally speaking, CBD oil added to a coffee or smoothie will probably take around 30 minutes before you start to feel anything.)
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A study published in Epilepsia in 2019 gave adults, prescribed with CBD for seizures, a single dose of 99% pure cannabidiol capsules on two occasions. The first saw the volunteers take the compound on an empty stomach. The second involved using CBD after consuming a high-fat breakfast containing 840-860 calories, approximately 600 of which came from fat.
Individuals with certain medical conditions may not process substances as well as healthier people. However, when it comes to CBD, a lack of homeostasis, or balance, in the ECS may speed up the rate of absorption.
The human body is remarkable, and our physiology can differ from person to person. This uniqueness comes into play when using CBD . If two individuals take the same CBD type, dose, and quality simultaneously, it may impact each person differently.
Homeostasis in the ECS.
The fact that CBD is highly fat-soluble can cause problems with absorption via topicals. The cannabinoids are repelled by your skin, which acts as an obstacle to absorption. However, a study published in 2004 found that combining CBD with about 30-33% ethanol helped make the cannabinoid more water-soluble.
Yet, the researchers also found that the effects seem to have a ceiling in doses between 400mg and 800mg. This is possibly because tissues become saturated and can’t absorb any more CBD.
The CBD in topicals doesn’t go beyond your skin, but transdermal products help diffuse the cannabinoid into the bloodstream.
Although not as popular as its THC equivalent, CBD flower is also available. You can purchase dozens of special marijuana strains high in CBD and low in THC. There are also hemp flower options too. A study published in Pharmaceuticals in 2020 found that smoking CBD resulted in peak plasma levels occurring within three minutes of inhalation.
There is a reason why CBD companies make sure they use a carrier such as MCT oil in their products. Fatty foods significantly impact cannabidiol absorption.
The CBD form you use plays a huge role in how quickly it absorbs into your system. We look into consumption methods in greater detail a little later on. However, first, let’s look at four other important factors influencing how quickly CBD gets to work.
The revealing truth about CBD…
A study published in the Journal of Clinical Pharmacology in 2019 analyzed the effect of cannabidiol on people with moderate to severe liver impairment. The researchers found that such individuals had greater blood CBD concentrations and lengthier clearance times after using 200mg of the cannabinoid than healthy control volunteers.
The method of consumption dictates the speed and level of absorption into your bloodstream. In general, the faster it gets to the bloodstream, the higher the bioavailability level.
This means that how CBD is absorbed is VERY important. Effective forms of CBD consumption not only get to the bloodstream faster, but they maintain substantial levels of the compound throughout the body. In other words, they offer high bioavailability. Additionally, the best ways to consume CBD involve bypassing the digestive system and metabolic process in the liver.
As CBD is fat-soluble, including a healthy fat source in your meal, such as fish high in omega-3 or avocado, can help even more.
However, combusting plant material can result in the release of carcinogenic substances. While a 2005 study suggested that cannabis smoke wasn’t causally linked to tobacco-related cancers, it was implicated in respiratory dysfunction.
Several factors influence the absorption rate, which is why a 2012 study by Schoedel and Harrison, published in Current Pharmaceutical Design , placed the bioavailability rate anywhere between 12% and 35%.
CBD, or cannabidiol, affects everyone differently. Independent variables such as dosage, body weight, and metabolism can influence your experience with the compound. Then there is the matter of how you consume CBD. The fastest method is intravenously, but since using a needle every day is not practical, inhalation via a vaporizer is the next best way. However, the full answer to the title question is much more complicated to explain.
When it comes to CBD absorption, size matters . A heavier individual may need more CBD to have the same effect as a lighter person who uses a lower dose. Reasons for this could be related to the strength of blood flow, fat stores, and more. While cannabidiol dosing guidelines are always broad, you’ll have to take into account your own body weight.
CBD must be absorbed into the bloodstream before being distributed through our endocannabinoid system (ECS). It is here that the cannabinoid interacts with the body’s receptors. This interaction is the driving force behind many of CBD’s perceived benefits.
Not all CBD products are created equally. We see sellers championing cannabidiol extracted from organic hemp, which is the bare minimum one would expect! Low-grade cannabidiol not only contains a smaller amount of CBD but also may include ingredients that reduce bioavailability.
As the name suggests, this involves consuming CBD through the mouth in a capsule, edible, or a CBD beverage . This method has a longer path to the bloodstream. It involves the salivary glands and the full stomach digestive process, which requires a journey through the liver, pancreas, and stomach.